DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and wrk-1

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001024651.1 Gene:wrk-1 / 181093 WormBaseID:WBGene00006942 Length:452 Species:Caenorhabditis elegans


Alignment Length:329 Identity:69/329 - (20%)
Similarity:126/329 - (38%) Gaps:59/329 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 GRDANLPCVVEHLGGYKVAWIHIDRQMILTIHRHVISRIPRYSITYTDNTWLLHVNQAHQDDRGY 122
            |....|.|.||   ...||.|......::.:...::.....|.|:...:|.:|.:.:....:...
 Worm    32 GESLTLRCEVE---DPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPINSAN 93

  Fly   123 YMCQVNTNPMISQVGYLQVVVPPNILDIESTPSSVAVRE----------------NQNINMTCRA 171
            |.|.: ..|.:|....::|.|        ..|:.|:|:.                .:|:.:||..
 Worm    94 YSCAL-AEPEVSVTFVIKVQV
--------FKPTQVSVKPLVVISPDTGVYHARVGEKNLVITCHV 149

  Fly   172 -DGFPAPKIIWRREDG---EEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSK 232
             :|.|.|.::|.::..   |:|..|.....:|       :|:|.::..|.|.|:|.|   .:.|.
 Worm   150 KEGNPKPGVVWTKQAAKLPEDIKREHGGARIV-------ITEVKKHHAGKYNCLAEN---IAGSD 204

  Fly   233 RIILDVEFSPMI--------WVPNQ--LVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMV-LPSK 286
            |..:|:..:..:        ||.|:  .:......:.:..|..:..|...:.|::|...: ...:
 Worm   205 RATIDIHV
AEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDE 269

  Fly   287 KY-KTDYTENSYRAHMK--LTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLP---STPSKQ 345
            |: ||..|......:.|  ||:.::....||:|.|...|.||.....:.|...|.|   |....:
 Worm   270 KFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVSGRPGPPQLSFDESE 334

  Fly   346 VTHT 349
            :|.|
 Worm   335 LTWT 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 17/84 (20%)
Ig 145..238 CDD:416386 23/112 (21%)
Ig strand A 145..149 CDD:409353 0/3 (0%)
Ig strand A' 154..159 CDD:409353 2/4 (50%)
Ig strand B 165..172 CDD:409353 2/7 (29%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 0/4 (0%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 0/5 (0%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 21/104 (20%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 1/6 (17%)
Ig strand C 272..277 CDD:409353 1/4 (25%)
Ig strand C' 281..283 CDD:409353 0/2 (0%)
Ig strand D 289..293 CDD:409353 2/3 (67%)
Ig strand E 295..305 CDD:409353 2/11 (18%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 1/8 (13%)
wrk-1NP_001024651.1 IG_like 25..113 CDD:214653 17/84 (20%)
IGc2 31..96 CDD:197706 13/66 (20%)
IG_like 132..212 CDD:214653 21/89 (24%)
IGc2 142..202 CDD:197706 18/69 (26%)
IG_like 235..320 CDD:214653 18/84 (21%)
Ig 245..318 CDD:143165 18/72 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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