DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-delta and rig-5

DIOPT Version :9

Sequence 1:	NP_001097508.2	Gene:	DIP-delta / 5740816	FlyBaseID:	FBgn0085420	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001251131.1	Gene:	rig-5 / 172791	WormBaseID:	WBGene00004372	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	326	Identity:	112/326 - (34%)
Similarity:	163/326 - (50%)	Gaps:	23/326 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PRFAQPIPNVTVA-VGRDANLPCVVEHLGGYKVAWIHIDR-QMILTIHRHVISRIPRYS----IT 102
            |...||..:..|| :|:|.:..|:|..||.:.||::..|. ..:|:....|..|..:|.    |.
Worm    84 PTIQQPSMSSAVALLGQDVDFTCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRNKYELKPRIG 148

  Fly   103 YTDNTWLLHVNQAHQDDRGYYMCQVNTNPMISQVGYLQVVVPPNILDIESTPSSVAVRENQNINM 167
            ...|.|:|.:....:.|||.|.||:||.|:....|.|.|.|||.:  ..|||::|.|||..|:::
Worm   149 DLHNEWVLTIKNVQESDRGNYSCQINTEPITLSTGELDVKVPPVV--SRSTPAAVEVREGNNVSL 211

  Fly   168 TCRADGFPAPKIIWRREDGEEIAVEKKK--KVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSV 230
            ||:|||.|.|.:||||:|.:.|......  ...|:...||.||||||..|..|||:|:||:||..
Worm   212 TCKADGNPTPTVIWRRQDRQIIRYNGATGFGASVFHGPVLHLTKVSRKHMSEYLCVASNGIPPDE 276

  Fly   231 SKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTDYT-E 294
            |..:.|.|.|.|::...::.|.|..|:...:.|.|||.|:..:.|..:...|..|......:| .
Worm   277 SWTVKLLVTFPPLVQAQSETVQASVGSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVS 341

  Fly   295 NSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPSTPSKQVTHTTVESRENNII 359
            ..|.:...|.|||:|...||.|||::||..|.....:.:          .|::|.  ....:|:|
Worm   342 GQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTL----------NQISHN--HFTNSNLI 394

  Fly   360 P 360
            |
Worm   395 P 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-delta	NP_001097508.2	IG	51..143	CDD:214652	31/97 (32%)
		Ig	145..238	CDD:416386	42/94 (45%)
		Ig strand A	145..149	CDD:409353	1/3 (33%)
		Ig strand A'	154..159	CDD:409353	2/4 (50%)
		Ig strand B	165..172	CDD:409353	2/6 (33%)
		Ig strand C	178..183	CDD:409353	2/4 (50%)
		Ig strand C'	185..187	CDD:409353	1/1 (100%)
		Ig strand D	195..199	CDD:409353	0/5 (0%)
		Ig strand E	203..209	CDD:409353	3/5 (60%)
		Ig strand F	216..223	CDD:409353	3/6 (50%)
		Ig strand G	230..238	CDD:409353	2/7 (29%)
		Ig	242..333	CDD:416386	27/91 (30%)
		Ig strand A'	250..253	CDD:409353	1/2 (50%)
		Ig strand B	259..266	CDD:409353	1/6 (17%)
		Ig strand C	272..277	CDD:409353	1/4 (25%)
		Ig strand C'	281..283	CDD:409353	0/1 (0%)
		Ig strand D	289..293	CDD:409353	0/3 (0%)
		Ig strand E	295..305	CDD:409353	2/9 (22%)
		Ig strand F	314..322	CDD:409353	4/7 (57%)
		Ig strand G	325..334	CDD:409353	1/8 (13%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	31/96 (32%)
		Ig_3	191..270	CDD:372822	36/80 (45%)
		IG	294..380	CDD:214652	26/85 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I6913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I2513
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm14489
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070