DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and Papln

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001192272.1 Gene:Papln / 170721 MGIID:2386139 Length:1302 Species:Mus musculus


Alignment Length:438 Identity:89/438 - (20%)
Similarity:146/438 - (33%) Gaps:141/438 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 EPRFAQPIPNVTVAVGRDANLPCVVEHLGGYKVAW------IHIDRQMILTIHRHVISRIPRYSI 101
            ||...|..|...|.:....|:|      ..::..|      |..:|..:......:|||:     
Mouse   932 EPSLVQAAPGQAVQLFCPGNIP------SEFQAGWQKEGRPISSNRYQLQADGSLIISRL----- 985

  Fly   102 TYTDNTWLLHVNQAHQDDRGYYMC------------QVNT--------------------NPMI- 133
                          ..:|.|.|.|            |:..                    ||.: 
Mouse   986 --------------RPEDAGIYSCGSHRPGHEPQEIQLRVTGGDMAVFPEGQPRHFPEPRNPDLG 1036

  Fly   134 ---------SQVGYLQVVVPPN-----ILDIEST-PSSVAVRENQNINMTCRADGFPAPKIIWRR 183
                     ::.|..:|:.|.:     .|.::.| |..|.....|.|.:||||:|||.|.|.|:|
Mouse  1037 HGPPHRGTGAEAGGHRVLSPSHPRPATRLRLDRTQPGVVDASPGQRIRLTCRAEGFPVPTIEWQR 1101

  Fly   184 EDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPS---VSKRIILDVEFS---P 242
             ||:.::..:.:   |.....|.:::|...:.|.|.|:|.||....   |..|::.::..:   |
Mouse  1102 -DGQLVSSPRHQ---VQPDGSLVISRVDVEDGGYYSCVAFNGQDRDQRWVQLRVLRELTITGLPP 1162

  Fly   243 MIWVPN----QLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYRAHMK- 302
            .:.|..    :|:...:|..|.            |.|..|.:.:          ..:.:|.|.. 
Mouse  1163 AVTVAEGDTARLLCVVAGESVN------------IRWSRNGLPI----------QADGHRVHQSP 1205

  Fly   303 ---LTIRNLQYGDFGNYRCISKNSLGETEGSIRV-YEIPLPSTPSKQVTHTTVESRENNIIPSSR 363
               |.|.||:..|.|:|.|.:.........|..| ..:|.|:..|:.:....::.      |...
Mouse  1206 DGTLLIHNLRPRDEGSYTCSAFRGSQAVSRSTEVKVALPAPAAQSRDLGKDCIDQ------PELA 1264

  Fly   364 NDTTKSLQTDVGYAMKNDLYPGSASSSSSGGSSSAASSSSSMQTSALP 411
            | ....||..:   ..|:.|           ||...:|.|..|.:|.|
Mouse  1265 N-CALILQAQL---CGNEYY-----------SSFCCASCSRFQPNAQP 1297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 19/139 (14%)
Ig 145..238 CDD:416386 30/101 (30%)
Ig strand A 145..149 CDD:409353 0/8 (0%)
Ig strand A' 154..159 CDD:409353 2/4 (50%)
Ig strand B 165..172 CDD:409353 4/6 (67%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 19/98 (19%)
Ig strand A' 250..253 CDD:409353 1/2 (50%)
Ig strand B 259..266 CDD:409353 1/6 (17%)
Ig strand C 272..277 CDD:409353 2/4 (50%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 3/13 (23%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 2/9 (22%)
PaplnNP_001192272.1 TSP1 30..81 CDD:214559
ADAM_spacer1 184..299 CDD:368694
TSP1 309..362 CDD:214559
TSP1 389..447 CDD:214559
TSP1 447..504 CDD:214559
TSP1 511..562 CDD:214559
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 563..648
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 694..737
Kunitz_BPTI 771..822 CDD:333766
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 822..924
Papilin_u7 831..922 CDD:374683
Ig 932..>995 CDD:386229 16/87 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1024..1064 5/39 (13%)
I-set 1070..1141 CDD:369462 27/74 (36%)
Ig 1157..1241 CDD:386229 20/105 (19%)
PLAC 1257..1289 CDD:370061 9/52 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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