DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-delta and ncam2

DIOPT Version :9

Sequence 1:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_571905.1 Gene:ncam2 / 114441 ZFINID:ZDB-GENE-010822-1 Length:795 Species:Danio rerio


Alignment Length:432 Identity:93/432 - (21%)
Similarity:162/432 - (37%) Gaps:102/432 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 RQMILTIHRHVISRIPRY----------SITYT---------DNTW------------------- 108
            |.:||.::...:..:|:.          |:|:|         |.||                   
Zfish   197 RNIILVVNVPPVVSVPQQSFNATADYGESVTFTCRAYGSPEPDVTWHRKGVQLQESERYVMRARG 261

  Fly   109 -LLHVNQAHQDDRGYYMCQV-NTNPMISQVGYLQVVVPPNILDIESTPSSVAVRENQNINMTCRA 171
             .|.|....|||.|.|.|:. |....:....:|:|.|.|:|..:.    :|...|.....::|:|
Zfish   262 TTLTVRNIQQDDGGSYTCRASNKAGEVEHELFLKVFVQPHITKLR----NVTAVEGSAAMISCKA 322

  Fly   172 DGFPAPKIIWRR-EDGEEIA---------VEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGV 226
            :|.|.|:|.||| .||...:         ||.:.:   |...:|.:..|..::.|.:.|.|.:.:
Zfish   323 EGEPLPEISWRRASDGHSFSDGDKSPDGRVEVRGR---YGESMLTIVVVKLSDWGRFDCEALSRI 384

  Fly   227 PPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTD 291
             ....|.:.||:|::|.....:.:..:..|..|.|.|...::|.|.:.| ....:.:||:     
Zfish   385 -GGHQKSMFLDIEYAPKFQANHTIFFSWEGNPVNISCDVMSNPPATMLW-RREKLTIPSE----- 442

  Fly   292 YTENSYRAHMK-----LTIRNLQYGDFGNYRCISKNSLG---------ETEGSIRVYEIPLPSTP 342
             ...:.|.:..     |.:..:...|||.|.|.::|::|         :.:.....|.:.|.|..
Zfish   443 -GAGNMRVYTAPGRSLLEVTPMSDRDFGRYNCTARNNIGMRFQEFILAQADVPSNPYSVRLSSVA 506

  Fly   343 SKQVTHTTVESRENNIIP-----------SSRN-DTTKSLQTDVGYAMKNDLYPGSA----SSSS 391
            .:..|.|..:...:..:|           ||:: ...|||.|.....:.| |.|.:.    .|:.
Zfish   507 QRVATVTFTKPDSHGGVPISHYLVKYKDISSQDWKDVKSLGTQTIVLLTN-LEPNTTYEVRVSAV 570

  Fly   392 SGGSSSAASSSSSMQTSALPGGVAGNSLSSMGSKGSLAIGKS 433
            :|......|.:.|.||..:      ...|....:|...:||:
Zfish   571 NGKGQGEFSHTESFQTLPI------REPSPPSVQGQRGVGKA 606

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 21/100 (21%)
Ig 145..238 CDD:416386 25/102 (25%)
Ig strand A 145..149 CDD:409353 2/3 (67%)
Ig strand A' 154..159 CDD:409353 1/4 (25%)
Ig strand B 165..172 CDD:409353 1/6 (17%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 2/6 (33%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 19/104 (18%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 3/6 (50%)
Ig strand C 272..277 CDD:409353 1/4 (25%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 2/14 (14%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 1/17 (6%)
ncam2NP_571905.1 Ig1_NCAM-2 20..111 CDD:143274
I-set 21..110 CDD:254352
IGc2 127..187 CDD:197706
Ig 213..299 CDD:299845 17/85 (20%)
I-set 213..296 CDD:254352 16/82 (20%)
Ig 298..395 CDD:299845 26/104 (25%)
I-set 300..393 CDD:254352 24/100 (24%)
IG_like 411..488 CDD:214653 18/83 (22%)
IGc2 412..480 CDD:197706 17/74 (23%)
FN3 494..586 CDD:238020 19/92 (21%)
fn3 <616..675 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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