DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and TOM71

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_011985.1	Gene:	TOM71 / 856517	SGDID:	S000001159	Length:	639	Species:	Saccharomyces cerevisiae

Alignment Length:	224	Identity:	50/224 - (22%)
Similarity:	89/224 - (39%)	Gaps:	46/224 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 NEEEAE---GQEKPKRSLKSSTITEESFIITERKTPIPVISAPTSSKEKSKPRTFNRIDRSKDRF 95
            |..::|   ||.:.:..||...               .|:|.....|:|...|..|...:|.:.|
Yeast    51 NRRQSEAFAGQNEDEADLKDDG---------------SVVSGSNKRKKKKNKRKRNNKAKSGEGF 100

  Fly    96 --PFMRQVEMDLDQ-RSKARLERERVAQNFRKLGNAEYRKGNYEAAMKVYTEAIENIRDSHILYI 157
              |.:...|.|:.| :..:..:|:..|...:..||..:...|:..|:|.|..|||...:..:.|.
Yeast   101 DYPSLPNGEPDIAQLKGLSPSQRQAYAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNEPVFYS 165

  Fly   158 NRALCFIKSGKFKRGIVDCDFVLNKLDEK--NLRAWMYRAMAYKGLN------------------ 202
            |.:.|:|.:|..::.|   :|....|:.|  :.:|.:.||.|.:.|.
Yeast   166 NISACYISTGDLEKVI---EFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVLSLNGDF 227

  Fly   203 DESNFENCVKYARKFNSKQMDFIDDFLEK 231
            |.::.|..::  |..|.:.|..:::.|.|
Yeast   228 DGASIEPMLE--RNLNKQAMKVLNENLSK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	18/65 (28%)
		TPR repeat	119..147	CDD:276809	8/27 (30%)
		TPR repeat	152..183	CDD:276809	7/30 (23%)
		TPR repeat	188..216	CDD:276809	7/45 (16%)
TOM71	NP_011985.1	3a0801s09	9..636	CDD:273380	50/224 (22%)
		TPR repeat	127..155	CDD:276809	8/27 (30%)
		TPR repeat	160..190	CDD:276809	8/32 (25%)
		TPR repeat	195..218	CDD:276809	5/22 (23%)
		TPR repeat	345..373	CDD:276809
		TPR repeat	378..406	CDD:276809
		TPR repeat	411..441	CDD:276809
		TPR repeat	446..471	CDD:276809
		TPR repeat	480..508	CDD:276809
		TPR repeat	513..559	CDD:276809
		TPR repeat	564..588	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870