DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and TOM70

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_014278.3	Gene:	TOM70 / 855602	SGDID:	S000005065	Length:	617	Species:	Saccharomyces cerevisiae

Alignment Length:	215	Identity:	48/215 - (22%)
Similarity:	84/215 - (39%)	Gaps:	48/215 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 ESFIITERKTPIPVISAPTSS--------------KEKSKPRTFNRIDRSKDR------------ 94
            :|| ||..||.|....|.|.:              :::.|..|.|: |..||.
Yeast     2 KSF-ITRNKTAILATVAATGTAIGAYYYYNQLQQQQQRGKKNTINK-DEKKDTKDSQKETEGAKK 64

  Fly    95 ---------FPFMRQVEMDLDQRSK-ARLERERVAQNFRKLGNAEYRKGNYEAAMKVYTEAIENI 149
                     :|.....|.|...::. ...|:::.|...:..||..:|...|:.|:|.|..|:| :
Yeast    65 STAPSNPPIYPVSSNGEPDFSNKANFTAEEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALE-L 128

  Fly   150 RDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKGLND--ESNFENCVK 212
            ::..:.|.|.:.|::..|..|: :|:......:|.....:..:.||.|.:||..  ::.|:..|.
Yeast   129 KEDPVFYSNLSACYVSVGDLKK-VVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVL 192

  Fly   213 YARKFNSKQMDFIDDFLEKL 232
                  |...||.|..:|.:
Yeast   193 ------SLNGDFNDASIEPM 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	17/65 (26%)
		TPR repeat	119..147	CDD:276809	9/27 (33%)
		TPR repeat	152..183	CDD:276809	6/30 (20%)
		TPR repeat	188..216	CDD:276809	7/29 (24%)
TOM70	NP_014278.3	3a0801s09	1..614	CDD:273380	48/215 (22%)
		TPR repeat	99..127	CDD:276809	9/27 (33%)
		TPR repeat	131..161	CDD:276809	6/30 (20%)
		TPR repeat	166..189	CDD:276809	6/22 (27%)
		TPR repeat	330..358	CDD:276809
		TPR repeat	363..391	CDD:276809
		TPR repeat	396..426	CDD:276809
		TPR repeat	431..459	CDD:276809
		TPR repeat	465..493	CDD:276809
		TPR repeat	498..537	CDD:276809
		TPR repeat	542..567	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870