DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and CNS1

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_009713.1	Gene:	CNS1 / 852452	SGDID:	S000000359	Length:	385	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	41/163 - (25%)
Similarity:	79/163 - (48%)	Gaps:	29/163 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 KPRTFNRIDRSKDRFPFM------------RQVEMDLDQRSKARLERERVAQNFRKLGNAEYRKG 133
            |.:|.:.|.:..:|.||.            ..||::..:......|...:|:||:|.||..|:..
Yeast    33 KDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAK 97

  Fly   134 NYEAAMKVYTEAI------ENIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWM 192
            .::.|.::|::.:      ::|.:|  ||.|||.|.::...::|.|.||...|. ::.||::.:.
Yeast    98 RFKDARELYSKGLAVECEDKSINES--LYANRAACELELKNYRRCIEDCSKALT-INPKNVKCYY 159

  Fly   193 YRAMAYKGLN--DESNFENCVKYARKFNSKQMD 223
            ..:.|:..||  :|:      |.|..|.::::|
Yeast   160 RTSKAFFQLNKLEEA------KSAATFANQRID 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	22/71 (31%)
		TPR repeat	119..147	CDD:276809	9/33 (27%)
		TPR repeat	152..183	CDD:276809	12/30 (40%)
		TPR repeat	188..216	CDD:276809	6/29 (21%)
CNS1	NP_009713.1	3a0801s09	68..>218	CDD:273380	33/128 (26%)
		TPR repeat	83..111	CDD:276809	9/27 (33%)
		TPR repeat	120..150	CDD:276809	12/32 (38%)
		Wheel	257..374	CDD:408742
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R218
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940