DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and stip1

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001007767.1	Gene:	stip1 / 493606	ZFINID:	ZDB-GENE-041121-17	Length:	542	Species:	Danio rerio

Alignment Length:	150	Identity:	41/150 - (27%)
Similarity:	72/150 - (48%)	Gaps:	6/150 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KEKSKPRTFNRI---DRSKDRFPFMRQVEMDLDQRSKARLERERVAQNFRKLGNAEYRKGNYEAA 138
            |.|...:.||:.   .|:.|.....::.|..|.::.|.......:|...:..||..::||:|..|
Zfish   314 KYKEAVQFFNKSLTEHRTPDVLKKCQEAEKILKEQEKVAYINPDLALEEKNKGNDAFQKGDYPLA 378

  Fly   139 MKVYTEAIENIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKGLND 203
            ||.|:|||:.......|:.|||.|:.|..:|:..:.||:..:| ||...::.:..:..|.:.:.|
Zfish   379 MKHYSEAIKRNPYDAKLFSNRAACYTKLLEFQLALKDCEECIN-LDSTFIKGYTRKGAALEAMKD 442

  Fly   204 ESNFENCVKYARKF--NSKQ 221
            .|...:..:.|.:.  |||:
Zfish   443 FSKAMDVYQKALELDSNSKE 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	24/65 (37%)
		TPR repeat	119..147	CDD:276809	12/27 (44%)
		TPR repeat	152..183	CDD:276809	10/30 (33%)
		TPR repeat	188..216	CDD:276809	4/27 (15%)
stip1	NP_001007767.1	TPR_11	7..69	CDD:290150
		TPR	7..37	CDD:197478
		TPR repeat	7..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR_11	40..103	CDD:290150
		TPR repeat	72..100	CDD:276809
		TPR_11	224..285	CDD:290150
		TPR repeat	228..252	CDD:276809
		TPR_1	230..257	CDD:278916
		TPR_12	254..327	CDD:290160	4/12 (33%)
		TPR repeat	257..287	CDD:276809
		TPR	299..327	CDD:197478	4/12 (33%)
		TPR repeat	299..326	CDD:276809	4/11 (36%)
		TPR_11	359..423	CDD:290150	23/64 (36%)
		TPR repeat	363..387	CDD:276809	11/23 (48%)
		TPR repeat	392..422	CDD:276809	10/30 (33%)
		TPR_1	427..459	CDD:278916	4/31 (13%)
		TPR repeat	427..455	CDD:276809	4/27 (15%)
		STI1	491..530	CDD:128966
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810