DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and Ttc12

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_006243066.1	Gene:	Ttc12 / 300696	RGDID:	1303264	Length:	723	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	60/224 - (26%)
Similarity:	106/224 - (47%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 EVVRLLENL-QVPNEEEAEGQEKPKRSLKSSTITEESFIITER------------KTPIPVISAP 73
            ::.|.|||: ::.|..:....:.|....|:...||:..::.||            ||.|....||
  Rat    27 DLQRFLENVDEITNLIQEMNSDDPFIQQKAVLDTEKKLLLMEREQEEDGCRTTLNKTMISPPQAP 91

  Fly    74 TSSKEKSKPRTFNRIDRSKDRFPFMRQVEMDLDQRSKARLERERVAQNFRKLGNAEYRKGNYEAA 138
            .::.|.:..             .|:..||.|..:|:|.|.|...:|...::.||..:.||:||.|
  Rat    92 ENANEMNPD-------------AFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVKGDYETA 143

  Fly   139 MKVYTEAIENIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKGLND 203
            :..|:|.:..::|..:||.|||..:||.|.:::.:||||:.| |.||...:|:.:...|:..|.:
  Rat   144 IFFYSEGLGKLKDMKVLYTNRAQAYIKLGDYQKALVDCDWAL-KCDENCTKAYFHMGKAHLALKN 207

  Fly   204 ESNFENCVKYARKFNSKQMDFIDDFLEKL 232
            .|..:.|.:...:.|.|....:.:.|.::
  Rat   208 YSKSKECYQKIGEINPKLKAQVKEHLNQV 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	25/65 (38%)
		TPR repeat	119..147	CDD:276809	10/27 (37%)
		TPR repeat	152..183	CDD:276809	13/30 (43%)
		TPR repeat	188..216	CDD:276809	5/27 (19%)
Ttc12	XP_006243066.1	TPR_11	124..189	CDD:290150	25/65 (38%)
		TPR repeat	124..152	CDD:276809	10/27 (37%)
		TPR repeat	157..187	CDD:276809	13/30 (43%)
		TPR_11	160..223	CDD:290150	21/63 (33%)
		TPR_1	161..191	CDD:278916	15/30 (50%)
		TPR repeat	192..217	CDD:276809	5/24 (21%)
		TPR_1	193..224	CDD:278916	6/30 (20%)
		ARM	631..723	CDD:237987
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005389
OrthoInspector	1	1.000	-	-		otm44459
orthoMCL	1	0.900	-	-		OOG6_108547
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710