DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34297 and Stip1

DIOPT Version :9

Sequence 1:	NP_001097696.1	Gene:	CG34297 / 5740802	FlyBaseID:	FBgn0085326	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_620266.1	Gene:	Stip1 / 192277	RGDID:	621599	Length:	543	Species:	Rattus norvegicus

Alignment Length:	157	Identity:	44/157 - (28%)
Similarity:	74/157 - (47%)	Gaps:	19/157 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 DRSKDRFPFMRQ---------VEMDLDQRSKARLERERVAQ-------NFRKLGNAEYRKGNYEA 137
            :|.||...|..:         |.....|..|...|:||:|.       ..:..||..::||:|..
  Rat   314 ERYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQ 378

  Fly   138 AMKVYTEAIE-NIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKGL 201
            |||.|||||: |.||:. ||.|||.|:.|..:|:..:.||:..: :|:...::.:..:|.|.:.:
  Rat   379 AMKHYTEAIKRNPRDAK-LYSNRAACYTKLLEFQLALKDCEECI-QLEPTFIKGYTRKAAALEAM 441

  Fly   202 NDESNFENCVKYARKFNSKQMDFIDDF 228
            .|.:...:..:.|...:|...:..|.:
  Rat   442 KDYTKAMDVYQKALDLDSSCKEAADGY 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34297	NP_001097696.1	TPR_11	119..185	CDD:290150	28/73 (38%)
		TPR repeat	119..147	CDD:276809	13/34 (38%)
		TPR repeat	152..183	CDD:276809	10/30 (33%)
		TPR repeat	188..216	CDD:276809	4/27 (15%)
Stip1	NP_620266.1	TPR 1	4..37
		3a0801s09	<7..532	CDD:273380	44/157 (28%)
		TPR repeat	7..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR 2	39..71
		TPR repeat	72..100	CDD:276809
		TPR 3	73..105
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..233
		Bipartite nuclear localization signal. /evidence=ECO:0000255	222..239
		TPR 4	225..258
		TPR repeat	229..253	CDD:276809
		TPR repeat	258..288	CDD:276809
		TPR 5	260..292
		TPR 6	300..333		4/18 (22%)
		TPR repeat	300..328	CDD:276809	4/13 (31%)
		TPR 7	360..393		14/32 (44%)
		TPR repeat	364..388	CDD:276809	12/23 (52%)
		TPR repeat	393..423	CDD:276809	11/31 (35%)
		TPR 8	395..427		11/33 (33%)
		TPR 9	428..461		5/32 (16%)
		TPR repeat	428..456	CDD:276809	4/27 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810