Protein Alignment CG34436 and PRSS1

DIOPT Version :10

• Sequence 1: NP_001097954.1
• Gene: CG34436 / 5740743
• FlyBaseID: FBgn0085465
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 59/258 - (22%)
• Similarity: 102/258 - (39%)
• Gaps: 59/258 - (22%)

  Fly    26 NCAEVSRLSNDIIFSRPWMALVLLPNKTCSGALIHKYFVITSASCVFNQERAIVRLGQLSIKQEH 90
            ||.|     |.:    |:...:......|.|:||::.:|:::..|.  :.|..||||     :.:
Human    29 NCEE-----NSV----PYQVSLNSGYHFCGGSLINEQWVVSAGHCY--KSRIQVRLG-----EHN 77

  Fly    91 IVSYSSDDYHVQSAYI--HRFYEKSNFEHDIALLELQNDVLYKAHIRPICLWLDKSDIDTQMFKR 153
            |.....::..:.:|.|  |..|::....:||.|::|.:..:..|.:..|.|........|:..
Human    78 IEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCL-- 140

  Fly   154 YETFRWG---------IDEKYILPAAKTSKIKHISQVKCENAFKLYPQNSHICAGY--KNKSKCV 207
              ...||         .||...|.|..      :||.|||.::.....::..|.|:  ..|..|.
Human   141 --ISGWGNTASSGADYPDELQCLDAPV------LSQAKCEASYPGKITSNMFCVGFLEGGKDSCQ 197

  Fly   208 -ETGSPLFKKIRYYTKIRYTLFGIQSYGE-----SRTCLYTDVTKYIDWIMGVIQNVNVIVSN 264
             ::|.|:.        ....|.|:.|:|:     ::..:||.|..|:.||.      |.|.:|
Human   198 GDSGGPVV--------CNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK------NTIAAN 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:473915	51/230 (22%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	54/243 (22%)