Protein Alignment CG34436 and KLK1

DIOPT Version :10

• Sequence 1: NP_001097954.1
• Gene: CG34436 / 5740743
• FlyBaseID: FBgn0085465
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 66/304 - (21%)
• Similarity: 112/304 - (36%)
• Gaps: 89/304 - (29%)

  Fly     6 CLAVLSWMLANQGSAQLLDQ------NCAEVSRLSNDIIFSRPWM-ALVLLPNKTCSGALIHKYF 63
            |||:   .|...|:|..:..      .|.:         .|:||. ||.......|.|.|:|:.:
Human     7 CLAL---SLGGTGAAPPIQSRIVGGWECEQ---------HSQPWQAALYHFSTFQCGGILVHRQW 59

  Fly    64 VITSASCVFNQERAIVRLGQLSI-KQEHIVSYSSDDYHVQSAYIHRFYEKS-----------NFE 116
            |:|:|.|:.:..:  :.||:.:: ..|:...:    .||..::.|..:..|           ::.
Human    60 VLTAAHCISDNYQ--LWLGRHNLFDDENTAQF----VHVSESFPHPGFNMSLLENHTRQADEDYS 118

  Fly   117 HDIALLELQN--DVLYKA-----------HIRPICLWLDKSDIDTQMFKRYETFRWGIDEKYILP 168
            ||:.||.|..  |.:..|           .:...||......|:.:.|...:..:. :|.| |||
Human   119 HDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQC-VDLK-ILP 181

  Fly   169 AAKTSKIKHISQVKCENAFKLYPQNSHICAGY--KNKSKCV-ETGSPLFKKIRYYTKIRYTLFGI 230
            ..:..| .|:.:|          .:..:|.|:  ..|..|| ::|.||.        ....|.|:
Human   182 NDECKK-AHVQKV----------TDFMLCVGHLEGGKDTCVGDSGGPLM--------CDGVLQGV 227

  Fly   231 QSYG------ESRTCLYTDVTKYIDWIMGVIQNVNVIVSNGENS 268
            .|:|      .::..:...|..|:.||...|         .|||
Human   228 TSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI---------AENS 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:473915	54/246 (22%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	56/267 (21%)