DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34436 and CG14760

DIOPT Version :9

Sequence 1:	NP_001097954.1	Gene:	CG34436 / 5740743	FlyBaseID:	FBgn0085465	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	53/245 - (21%)
Similarity:	103/245 - (42%)	Gaps:	43/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IIFSRPWMALVLLPNK---TCSGALIHKYFVITSASCVFNQE-------RAIVRLGQLSIKQEHI 91
            ::...|.||.||....   .|..|:||..:::::|.|....|       |.:|....|:...|
  Fly   284 VLHEFPPMAGVLTKKHGKVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFE-- 346

  Fly    92 VSYSSDDYHVQSAYIHRFYEKSNFE--HDIALLELQNDVLYKAHIRPICLWLDKSDIDTQ----- 149
             ::::..|.:.:..:|..:.:::.:  :|||:|:.:..:::..|:.|.||.|...: |.|
  Fly   347 -TFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGE-DGQKLPLA 409

  Fly   150 ----MFKRYETFRWGIDEKYILPAAKTSKIKHISQVKCENAFK----LYPQNSHICAGYKNKSKC 206
                :...:.|..:|..:.:.|..|   .:..|...:|..|..    |.|..  .|.....:..|
  Fly   410 GHQVVAAGWGTTSYGGPQTHRLLKA---TLDVIDGRRCRQALSSAGGLPPHT--FCTYTPGRDTC 469

  Fly   207 -VETGSPLFKKIRYYTKIRYTLFGIQSYGES----RTCLYTDVTKYIDWI 251
             .::|..|:::|..    |....||.|:|::    :..:.|.|..:|.||
  Fly   470 QYDSGGALYERING----RLMAVGIVSFGQACAAQQPSVNTRVASFIKWI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:304450	53/242 (22%)
CG34436	NP_001097954.1	Tryp_SPc	40..251	CDD:214473	51/240 (21%)
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	53/245 (22%)
		Tryp_SPc	281..515	CDD:214473	51/243 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455910
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030