Protein Alignment CG34347 and Frmd6

DIOPT Version :10

• Sequence 1: NP_001368952.1
• Gene: CG34347 / 5740668
• FlyBaseID: FBgn0085376
• Length: 1519
• Species: Drosophila melanogaster
• Sequence 2: NP_001386220.1
• Gene: Frmd6 / 257646
• RGDID: 727810
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 107/591 - (18%)
• Similarity: 192/591 - (32%)
• Gaps: 220/591 - (37%)

  Fly     3 CLCRPS-RIMSVRINLLDETEFIHEIKDDLPGQALLDVVFARLNLIETSYFGIRYIDEENQTH-- 64
            |:..|: :.:|:.||:   ....|:         ||..|...|.|.::..||:..|  :|..|
  Rat    19 CIFLPNDKSVSIIINV---KILCHQ---------LLVQVCDLLRLKDSHLFGLSVI--QNNEHVY 69

  Fly    65 --------------WLDPASRISR--------QLKPKSDPYDLYFGVKFYAADPCKLLEEITRYQ 107
                          |...||::.:        |..|   |..::|.|::|..:...:.:.|.||.
  Rat    70 MELSQKLYKYCPKEWKKEASKVRQYEVTWGIDQFGP---PMIIHFRVQYYVENGKLISDRIARYY 131

  Fly   108 LFLQVKQDVLQGRLPVAFELAAELGAFVVQSELGDYDQRRHSKGYVSEFRLLP------NQSNEL 166
            .:..:::.||..:..:..|....|.||.:|::||::.::.|...|.......|      ...:.:
  Rat   132 YYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRKVHHGDYFEPEAYFPAWVVSKRGKDYI 196

  Fly   167 ETRVSELHQQLKGMSPSSAELNYLDK--------VKWHDMYGVDLHPVLGEDSVEYFLGLTPSGI 223
            ...:..:|:....::.|.|.|.|:.:        :.::.:| .|...|.|    ...||||..||
  Rat   197 LKHIPNMHRDQFALTASEAYLKYIKEAVRLDDVAIHYYRLY-KDKREVEG----SLTLGLTMRGI 256

  Fly   224 VVLRN----KTTVAHYYWPRIAKVYYKGRYFMLRISDKNNELSTYGFETPRK----SAC----KH 276
            .:.:|    |..:..:.|..:.|:.:.|:.|         |:...|..:.||    :.|    :|
  Rat   257 QIFQNLEEEKQLLYDFPWTNVGKLVFVGKKF---------EILPDGLPSARKLVYYTGCPTRSRH 312

  Fly   277 LWRCCVEHHAFFRQVRVAPLPSSQSHAADLFQLGSRFRHSRPDKQTEKDALSAGRSPPAFTRTPS 341
            |.:.....|..:  :.:.|:                .||.|..::.|:
  Rat   313 LLQLLSNSHRLY--MNLQPV----------------LRHLRKQEENEE----------------- 342

  Fly   342 KRQPRRVIDDFFNSNGNGNGNGNGNGNGHGHGGSGAGTLGGGSHMGNRPLPQPGMGTISNNYDSP 406
            |:|.|.                                                 ..||:|.|
  Rat   343 KKQYRE-------------------------------------------------SYISDNLD-- 356

  Fly   407 YRSTYSIPTSLGIRPCHQQQNNNSSSYNNNSGGNLQTPDSPRSTRSAPWPRSQQRSLFGHNPSSP 471
                      |.:.|..::     |..:.:|.|::                 :.:.|..|:.:|
  Rat   357 ----------LDMDPLEKR-----SRASGSSAGSM-----------------KHKRLSRHSTAS- 388

  Fly   472 RSVRSASTAGGGLHHHHSHHSHGHGTSHHPHHQSSSAGATSSTSHHHRQQRASSSSASHQQQRYR 536
                           |.|.|:.|..|...|.......|.:.|..  ||:.:..||..||...  .
  Rat   389 ---------------HSSSHTSGIETDTKPRDPGPEDGYSGSVM--HRKLKTCSSMTSHGSS--H 434

  Fly   537 SSSVES 542
            :|.|||
  Rat   435 TSGVES 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34347	NP_001368952.1	B41	13..204	CDD:214604	44/228 (19%)
		FERM_C_NBL4_NBL5	200..289	CDD:270007	23/100 (23%)
		FA	305..347	CDD:462582	6/41 (15%)
		RSRP	596..>694	CDD:293674
Frmd6	NP_001386220.1	Ubl1_cv_Nsp3_N-like	15..120	CDD:475130	25/117 (21%)
		FERM_M	118..234	CDD:459788	20/115 (17%)
		FERM_C_FRMD1_FRMD6	227..335	CDD:270006	27/139 (19%)