DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34457 and PRSS1

DIOPT Version :9

Sequence 1:	NP_001097339.1	Gene:	CG34457 / 5740661	FlyBaseID:	FBgn0085486	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	165	Identity:	30/165 - (18%)
Similarity:	49/165 - (29%)	Gaps:	62/165 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 LNAALSVVINEKVVRKSQSINEDCELSVAPSKRPCVRNSFKIVSGDGRDRTGENIKYGQRFQLQC 159
            |.:..|.||::|                 ||:..|.|                    |....:||
Human    11 LGSVFSAVISQK-----------------PSRDICQR--------------------GTSLTIQC 38

  Fly   160 MASEHDPIVLY--SGPKR-----CNLQQGVHATYLSHKNGEL---------NLNLGLVHRSKLSC 208
            .......::.:  ..|.:     ....||..|||   ::|.:         ||....:..|.:|.
Human    39 QVDSQVTMMFWYRQQPGQSLTLIATANQGSEATY---ESGFVIDKFPISRPNLTFSTLTVSNMSP 100

  Fly   209 PDNDIPIAYTNWFCRHVNPKQRFESEGEDIPSNSP 243
            .|:.|      :.|...:..:..:...|..|..||
Human   101 EDSSI------YLCSVEDTVRGTDQRSEQEPQLSP 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34457	NP_001097339.1	None
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845	23/145 (16%)
		IG_like	29..113	CDD:214653	18/112 (16%)
		Tryp_SPc	248..464	CDD:214473
		Tryp_SPc	249..467	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900