DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34457 and CFAP161

DIOPT Version :9

Sequence 1:	NP_001097339.1	Gene:	CG34457 / 5740661	FlyBaseID:	FBgn0085486	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_775799.2	Gene:	CFAP161 / 161502	HGNCID:	26782	Length:	301	Species:	Homo sapiens

Alignment Length:	306	Identity:	90/306 - (29%)
Similarity:	144/306 - (47%)	Gaps:	51/306 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FQPSVRIGNWVEENCLEEDKIVNFKKQRDRGELLVEKARTLYDNFHKEIVLAAPKQTII-FGAIV 78
            :.|.||||||.|:..|||:.:.:|.::||:|:||::::|.|..|..:.:.|:..:...| :|..|
Human     6 YGPGVRIGNWNEDVYLEEELMKDFLEKRDKGKLLIQRSRRLKQNLLRPMQLSVTEDGYIHYGDKV 70

  Fly    79 QLMPIHINISDMDT---TDLNAALSVVINEKVVRK--SQSINEDCELSVAPSKRPCVRNSFKIVS 138
            .|    :|..|.||   ..|...||:.:....::.  ...:...|.||...:|.|..||:|.|:|
Human    71 ML----VNPDDPDTEADVFLRGDLSLCMTPDEIQSHLKDELEVPCGLSAVQAKTPIGRNTFIILS 131

  Fly   139 GDGRDRTGENIKYGQRF----------QLQCMASEHDPIVLYSGPKRCNLQQGVHATYLSHKNGE 193
            .. ||.||:.::|||.|          ::..::|:|.  .|....||..||:......:||.|
Human   132 VH-RDATGQVLRYGQDFCLGITGGFDNKMLYLSSDHR--TLLKSSKRSWLQEVYLTDEVSHVN-- 191

  Fly   194 LNLNLGLVHRSKLSCPDNDIPIAYTNWFCRHVNPKQRFESEGEDIPSNSPLVIVHATTNRNLAA- 257
                          |           |.....:|:.|.|.||..:|:|:.::|.|..|||.|||
Human   192 --------------C-----------WQAAFPDPQLRLEYEGFPVPANAKILINHCHTNRGLAAH 231

  Fly   258 ENVLIQTLFGPEFLVSVQNYRNIYRHEIWKNVWMISNGHQTGSKSA 303
            .::.:.|.||.|..|....|.:.:|.|..:|.||:..|:...:.|:
Human   232 RHLFLSTYFGKEAEVVAHTYLDSHRVEKPRNHWMLVTGNPRDASSS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34457	NP_001097339.1	None
CFAP161	NP_775799.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	269..301		2/9 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159509
Domainoid	1	1.000	109	1.000	Domainoid score	I6372
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12605
Inparanoid	1	1.050	109	1.000	Inparanoid score	I4904
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56406
OrthoDB	1	1.010	-	-		D404512at33208
OrthoFinder	1	1.000	-	-		FOG0008126
OrthoInspector	1	1.000	-	-		otm40308
orthoMCL	1	0.900	-	-		OOG6_104967
Panther	1	1.100	-	-	O	PTHR24274
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5257
SonicParanoid	1	1.000	-	-		X6078
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.940