DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nvd and TIC55-II

DIOPT Version :9

Sequence 1:	NP_001097670.1	Gene:	nvd / 5740633	FlyBaseID:	FBgn0287185	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_180055.1	Gene:	TIC55-II / 817019	AraportID:	AT2G24820	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	82/441 - (18%)
Similarity:	154/441 - (34%)	Gaps:	142/441 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 FLRKTENVVCYNHKR----DTINRLRKLK------------------------IQKIIELPP-PY 93
            |.:.|...:.:||:.    .|..|||.|:                        .:|.:|:.. .:
plant    20 FTKVTPTPIIHNHRSTCTIPTKPRLRLLRRSAVAGTAVSDQTEGGGDVLLNPEEEKRVEVADYDW 84

  Fly    94 PNGWYGILKSSQLKAGEATCVSCLGEDLVIFRSKKDIVFILDAYCPHLGANLGIGGSVADDCVIC 158
            ...||.:..:..:.......::.....:|:::..:..:...:..|||..|.|. .|.:.|..:.|
plant    85 TEEWYPLYLTKNVPEDAPLGLTVYDRQIVLYKDGEGTLRCYEDRCPHRLAKLS-EGQLIDGRLEC 148

  Fly   159 PFHQWKFRGTDGLCINIPY---STSVPKGSKLKKWISQEVDGFIFIWYHAE----QTELPWDLPV 216
            .:|.|:|.| :|.|:.||.   |..:||.:.:|.:..::..|.:::|...:    ..:|||
plant   149 LYHGWQFEG-EGKCVKIPQLPASAKIPKAACVKTYEVKDSQGVVWVWMSTKTPPNPEKLPW---- 208

  Fly   217 PMGEIDDTFVYHGHNEFYINCHIQEIP-------ENGADIAHFNAIHKKNFIN------------ 262
                 .:.|...|   |:......|:|       ||..|.||....|.:....
plant   209 -----FENFARPG---FFDISTTHELPYDHSILLENLMDPAHVPISHDRTDFTAKREDAQPLVFE 265

  Fly   263 ----------GSWAQKKRLFGLGSHHWKARWSPFTGKLKYLAEVNLSHTFKLFGK-------FGC 310
                      |:|.::|. .|.||:           .|::.|...|.:..:..||       .|.
plant   266 VTERSNRGFAGTWGREKE-GGKGSN-----------LLRFDAPCVLQNNREFEGKDGVKNYFSGL 318

  Fly   311 FRMEVSGKQIGPSIVCLEVNSYTFGKIKVFQYITPIEPMLQKVVHEFYGPRWIAPLMKIFIYGES 375
            |....:|:  |.|::.:.     ||       :|...|::..:      |:|      .:.....
plant   319 FLCRPTGQ--GKSMLIVR-----FG-------VTKRSPLVSVL------PQW------FWHQNAC 357

  Fly   376 LMFERDIKIWNHKVFNRNPILAKE--------------DASIKKFRLWFSQ 412
            .:||:|:..    :.::|.:|.||              |..:.::|.|..:
plant   358 KVFEQDMGF----LSSQNEVLMKEKVPTKDLYLNLKSSDTWVAEYRKWMDK 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nvd	NP_001097670.1	Rieske_RO_Alpha_N	97..210	CDD:239551	25/119 (21%)
TIC55-II	NP_180055.1	PLN02518	1..533	CDD:215283	82/441 (19%)
TIC55-II	NP_180055.1	Rieske_RO_Alpha_Tic55	71..204	CDD:239830	27/134 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	43	1.000	Domainoid score	I4734
eggNOG	1	0.900	-	-		E1_COG4638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1199207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920