DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nvd and zgc:92275

DIOPT Version :9

Sequence 1:	NP_001097670.1	Gene:	nvd / 5740633	FlyBaseID:	FBgn0287185	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001002612.1	Gene:	zgc:92275 / 436885	ZFINID:	ZDB-GENE-040718-356	Length:	460	Species:	Danio rerio

Alignment Length:	402	Identity:	148/402 - (36%)
Similarity:	221/402 - (54%)	Gaps:	45/402 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IYWIFFVPLEWKKDLDNEKWSFLRKTENVVCY-----NHKRDTINRLRKLKIQKIIELPPPYPNG 96
            :|.:.|.|||..:.:|.            |.|     ..:....|.:|:.:  |..||||.||||
Zfish    72 LYRLLFAPLELLRGVDE------------VGYIAEDGRSRAQAANEVRRRR--KTGELPPVYPNG 122

  Fly    97 WYGILKSSQLKAGEATCVSCLGEDLVIFRSKKDIVFILDAYCPHLGANLGIGGSVADDCVICPFH 161
            ||.:|.|..|:.|:...|:.||:.:.:||.:....:::|||||||||||.:||.|...|:.||||
Zfish   123 WYRVLDSHMLERGDVKSVTVLGQQVAVFRGQDGKAYVVDAYCPHLGANLAVGGRVVGGCIECPFH 187

  Fly   162 QWKFRGTDGLCINIPYSTSVPKGSKLKKWISQEVDGFIFIWYHAEQTELPWDLP----VPMGEID 222
            .|:|||.||.|:.|||:..||:.:|::.|.|.|::|.:.:|:|.:..|..|.:|    :..||
Zfish   188 GWQFRGVDGRCVKIPYADKVPEFAKVRCWPSCEINGLVLVWFHCDGLEPSWRVPEQSQITRGE-- 250

  Fly   223 DTFVYHGHNEFYINCHIQEIPENGADIAHFNAIHKKNFING---------SWAQKKRLFGLGSHH 278
              :||.|..|.:||.||:|||||.|||||...:|....::|         :|...:       |.
Zfish   251 --WVYRGRTEHFINAHIEEIPENAADIAHLAHLHTPGIVSGVDLRYTNSKTWEFIR-------HD 306

  Fly   279 WKARWSPFTGKLKYLAEVNLSHTFKLFGK-FGCFRMEVSGKQIGPSIVCLEVNSYTFGKIKVFQY 342
            ||..|.|.....|:.:::.:.|...:||: :....::|..:|:||.:|.|.......|:..:...
Zfish   307 WKVEWKPEPEPNKHCSQMLVKHALTVFGRHWPLLDLDVLARQVGPGVVFLLFEHSFLGRGVIMHC 371

  Fly   343 ITPIEPMLQKVVHEFYGPRWIAPLM-KIFIYGESLMFERDIKIWNHKVFNRNPILAKEDASIKKF 406
            :||:||:||.|.|..:....|.||: |..:..|.:.||||:.|||:|.:...|:|.|||::|:|.
Zfish   372 VTPVEPLLQCVSHTIFYQSSIPPLVPKFILRAECIQFERDVMIWNNKTYISKPMLVKEDSAIQKH 436

  Fly   407 RLWFSQFYSSNS 418
            |.|||||||.||
Zfish   437 RRWFSQFYSENS 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nvd	NP_001097670.1	Rieske_RO_Alpha_N	97..210	CDD:239551	49/112 (44%)
zgc:92275	NP_001002612.1	Rieske_RO_Alpha_N	123..236	CDD:239551	49/112 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580826
Domainoid	1	1.000	171	1.000	Domainoid score	I3711
eggNOG	1	0.900	-	-		E1_COG4638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50774
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2763
OMA	1	1.010	-	-		QHG63760
OrthoDB	1	1.010	-	-		D1199207at2759
OrthoFinder	1	1.000	-	-		FOG0009655
OrthoInspector	1	1.000	-	-		oto39305
orthoMCL	1	0.900	-	-		OOG6_104541
Panther	1	1.100	-	-	LDO	PTHR21266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16953
SonicParanoid	1	1.000	-	-		X5524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800