Protein Alignment CG43795 and smog

DIOPT Version :10

• Sequence 1: NP_001097435.2
• Gene: CG43795 / 5740629
• FlyBaseID: FBgn0264339
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Alignment Length: 1136
• Identity: 231/1136 - (20%)
• Similarity: 400/1136 - (35%)
• Gaps: 286/1136 - (25%)

  Fly   122 RKLHKKKINESIRKSVDKSLGLRHTPKNHRSLAEAEHLQGRPASEDAEDTA---LSEVMQLADEI 183
            :|.|:.:.|..: :|..:|....|:.::|.:..:.:..| |..|..|...|   |||..:.  .|
  Fly    35 KKCHQNQTNTQV-QSTQRSNCSSHSDRDHLTNQQKQQNQ-RTNSATAASAAAATLSESTRC--NI 95

  Fly   184 ELESSFVTAAPTGDPDIGVKQARQFVRDEANYQEDDDDTIDDDEELDEEEEEAPMSTTIKPKIAS 248
            .:.||..:::.|        ::.:.:|:.::......:|:.....|        :...:....||
  Fly    96 IISSSSSSSSST--------KSSKNIREPSSSSSTQLNTLYSLLVL--------LIVGLATATAS 144

  Fly   249 TRLLPVNGTWQR-------MGTISRDSPPESDYDSNALDNAQEDEEEEEGQPFGKLLPLNESLAT 306
            ....|.:..:.|       :....|...|:|.....:|.:......:..|..|.:|.|...|::.
  Fly   145 PSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDFDELTPTASSVSA 209

  Fly   307 TEWMDDGAQREPEAEARSQAASMEVKQISFDSDGDSDSEAGLDTSEVTMDDGYPPDAQVDDKTKQ 371
            ....:....|:..|...:.|.:..|..:    |..:.:.|..|.:......|..|:.:.:.|..:
  Fly   210 LSRAERFRLRKRSATPTTPATAAGVTSL----DVATAAAAATDAAAKDAGSGKKPEEKCEPKVLE 270

  Fly   372 LVIGDVEEDSGDNMESNQFTADVINARDSKIDLVSKFLQYIEQQHLMGSNCVAGTSLNLGEGVVD 436
            .:..:...|..|..|                |...:|:::     |.|....|.|.:.:.|
  Fly   271 TLPDEPFYDYTDIAE----------------DAARQFIEF-----LSGKFPNANTPIAIDE---- 310

  Fly   437 RYAQDRFRVEAEVAVNRANMLTRIFKTTGRSVQEDVNLLHASVLS------MVEFDDDIFAAGNC 495
                   ...|||: .|||.:      ...::.||.|||..::.:      :|:|.|::
  Fly   311 -------PTRAEVS-RRANGI------ASYALNEDDNLLAFAIAAPSIHTVVVKFRDNV------ 355

  Fly   496 FDWNEHPAQPGLFCPFAYRLPPPNLGAVFAKDLAMEYHYLGNTSEWFFLARKNAEKVIARNEQYL 560
                              .:||         |......|||:                     |.
  Fly   356 ------------------TIPP---------DQVHNKAYLGS---------------------YW 372

  Fly   561 KSFHLYSNRTEERIEDDTLAVKYEDGRWSKPYYDCGGGNI----WMLTYTVPFFGYENGTYHFKG 621
            :......|.|:...|            |..|:.||   |:    |:..:.:.|     ..:..|.
  Fly   373 RELGAAWNSTDGTQE------------WGAPFRDC---NLLTRRWLWPFRISF-----SEHRIKV 417

  Fly   622 TSGIDIDLRRVDIDQCPQRHTPGTKRPLNIFAGTDKCKQRTTMCEAIMGL-GFRRGSYKCLCRKG 685
            .:...|   ..|.|.|    ..|.:   .:|.....|.:.||.|...... ...|..|.||||:.
  Fly   418 VAAAFI---AADEDVC----NDGLE---EVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRES 472

  Fly   686 FYFPDIVSQHKFFNGSLLE--EEYEKLMLGKNSTYNSNSEYECLPCAEGCDSCEDSSPCIA---- 744
            :|.|:...|.  |.|..:|  |.|:              .|.|:||..||.:|:.:..|:.
  Fly   473 YYLPNSTLQG--FRGDRVELSEGYD--------------NYSCIPCPGGCTNCDSNGVCLTFQEE 521

  Fly   745 -ALNWPMRTSILA--------LACIVIGLLPPAAWFTFRYQQVKVVRAASPALLRVIALGAFFIY 800
             .||......:|.        |.|||:|::      .||.::.|.:.:....:|..|.||...:|
  Fly   522 EVLNVDACLRLLVAIVLGACILCCIVLGVI------VFRQRKCKAIASGMWTVLETILLGIVLLY 580

  Fly   801 CTNIVMYPNPNLYTCTARIWLREIGFSLTYGALMLKTWRISVIFRVRSAKAVKITDAALLKRLGI 865
            .:..|.:...:...|....||||:||...|||::||.:|..|.||.|.|....:.|..|||.||.
  Fly   581 ASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVDLLKYLGT 645

  Fly   866 ICGAIGTCLLVRTLVSPPDVVVGRTADDLK---AFLCKTDWWDYTFTSMEVLFLAWGVRLCIMVR 927
            :..|: .|.:.....|..|::.....:.|:   ...|....|:....:.|:|.|.:|:.|.|..|
  Fly   646 MVFAV-ICYMAAFTASSLDLLESAQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASR 709

  Fly   928 KAPSEFNESRFISMAIYNEFLLTCFLNVSMLFLQ----SPANPDLLYIIFFCHTQLTVTLLLALI 988
            .|.::|.|.:|:..|:..|||::.    |..||:    ...:|..:.:..|..:|||.:..|.||
  Fly   710 NANTQFRERQFLVTALTLEFLVSS----SFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLI 770

  Fly   989 FGSKVY------------IVLR------SGKSHQENIGMGTKASGAKFNFRPQVRTFANPSSVTT 1035
            |..|::            :.:|      .|.||.....:|...:|.         ...:| .:..
  Fly   771 FVPKLWYQHKQVRSLAYDLSIRLPVDAFKGTSHDAGQRLGGGYAGL---------CLGDP-DIGE 825

  Fly  1036 STVPVAAETKLSDQEALEEIRQLSMQLQRIQEMAPPKGVAVMTISSLLDGLKTPGGLMVVAAAAG 1100
            .|:     :::|.::...|:::|..||:            :|...:|..  ..|.    ::...|
  Fly   826 LTI-----SEMSPEDIRAELKRLYTQLE------------IMKNKTLRQ--DNPH----ISKRRG 867

  Fly  1101 ATAQGHSAANRQSALPLLALNVEMQKYSQQNNNSNGGRGSGRTSIPTMVLETPPSSTP-PSAAYE 1164
            ....||.             ...:||...::...:....|.:......:.|..||.|| .|....
  Fly   868 GRKAGHR-------------RFSLQKKGSKDKALSAKHRSNKHHQDIEITEAEPSRTPEDSVCSA 919

  Fly  1165 ERAVNT--ELSGDDFREQLLRRTADGHIICS 1193
            |...:|  |:||  ....:|..:...|.:.|
  Fly   920 EGPTDTYAEISG--VSHSMLSHSMVSHSVVS 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43795	NP_001097435.2	PDC1_MCP_like	448..629	CDD:350338	32/190 (17%)
		7tmC_GPR158-like	749..998	CDD:320420	74/275 (27%)
		TM helix 1	749..774	CDD:320420	6/32 (19%)
		TM helix 2	786..807	CDD:320420	6/20 (30%)
		TM helix 3	816..840	CDD:320420	11/23 (48%)
		TM helix 4	859..879	CDD:320420	7/19 (37%)
		TM helix 5	901..927	CDD:320420	7/25 (28%)
		TM helix 6	935..958	CDD:320420	7/22 (32%)
		TM helix 7	967..992	CDD:320420	8/24 (33%)
smog	NP_001245881.1	7tmC_GPR158-like	529..780	CDD:320420	74/261 (28%)
		TM helix 1	529..554	CDD:320420	6/30 (20%)
		TM helix 2	566..587	CDD:320420	6/20 (30%)
		TM helix 3	596..620	CDD:320420	11/23 (48%)
		TM helix 4	639..659	CDD:320420	7/20 (35%)
		TM helix 5	683..709	CDD:320420	7/25 (28%)
		TM helix 6	717..740	CDD:320420	9/26 (35%)
		TM helix 7	749..774	CDD:320420	8/24 (33%)