DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc20 and hscb

DIOPT Version :9

Sequence 1:	NP_001097616.1	Gene:	Hsc20 / 5740624	FlyBaseID:	FBgn0263606	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001072422.2	Gene:	hscb / 779876	XenbaseID:	XB-GENE-5793329	Length:	268	Species:	Xenopus tropicalis

Alignment Length:	227	Identity:	74/227 - (32%)
Similarity:	127/227 - (55%)	Gaps:	10/227 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KSAVKATNYTPLVRNAAQFNQFQLPEIRKFSVES-SPACWNCQKKSELKQNMICSDCGHLQDVNS 72
            |||..|.:.:.| |::..::      :|.|.|.| |..||.||.:.. :..:.|..|..||..:.
Frog    47 KSATSAMSRSTL-RSSCTYS------LRSFCVTSQSRLCWRCQAEMS-RAELFCPTCTSLQPPDE 103

  Fly    73 GINYFKLLSFPIQFSLESQKLTRSFRQLQTIVHPDKYSNKTSREQTNSSDWSSLINKAYKTLSTP 137
            ..::|::|.....|::::|:|.|.:|.||.::|||.:|.|:..|:..|...|:::|||||||.:|
Frog   104 SKDFFQVLDCEKSFNVDTQELQRKYRNLQRLLHPDFFSQKSESERNISEKQSTVVNKAYKTLLSP 168

  Fly   138 IDRGQYLLQLEGEQMPQD-NSALNKEFLMAMMERNEEVEDAEDTQTLENLNIQLIKELEEMARKL 201
            :.||.|||.|.|..:.:. :..::.:||..::|.||::.|||....:|.:...:.::|..:.:.|
Frog   169 LKRGVYLLSLNGITLKEGADDEVDTQFLFDILELNEQLNDAETKDDIEEVGHFVQEQLVSLTKDL 233

  Fly   202 NALFDSKDLSGVKETLVEMKYLLSIQNSIKQK 233
            ...|...||...|..|.:|||..:||:.:|:|
Frog   234 RKAFQQGDLQEAKILLAKMKYFSNIQDQVKKK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc20	NP_001097616.1	hscB	75..239	CDD:235133	55/160 (34%)
		DnaJ	75..135	CDD:99751	23/59 (39%)
		HSCB_C	159..231	CDD:285042	21/71 (30%)
hscb	NP_001072422.2	hscB	106..262	CDD:179914	53/155 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I9915
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13945
Inparanoid	1	1.050	114	1.000	Inparanoid score	I4697
OMA	1	1.010	-	-		QHG54294
OrthoDB	1	1.010	-	-		D1129824at2759
OrthoFinder	1	1.000	-	-		FOG0004407
OrthoInspector	1	1.000	-	-		oto102545
Panther	1	1.100	-	-	LDO	PTHR14021
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3856
SonicParanoid	1	1.000	-	-		X4795
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110