Protein Alignment CG34290 and TMPRSS3

DIOPT Version :10

• Sequence 1: NP_001097899.2
• Gene: CG34290 / 5740609
• FlyBaseID: FBgn0085319
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_076927.1
• Gene: TMPRSS3 / 64699
• HGNCID: 11877
• Length: 454
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 91/300 - (30%)
• Similarity: 126/300 - (42%)
• Gaps: 68/300 - (22%)

  Fly    16 LLHSLFIISVLESCHAVP---------------IVGGRIVSTVGSSTSKYPFMVSLQDVITRNTT 65
            |.||:::.....|.|.|.               ||||.:     |..|::|:..|||
Human   184 LHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNM-----SLLSQWPWQASLQ-------- 235

  Fly    66 NGVSYQ--HFCGGSLISDRWILSAAHCV--------WRKNIHYIAAFIGYENIENIGQLQPYGLE 120
                :|  |.||||:|:..||::|||||        |...:..::.      ::|     |....
Human   236 ----FQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSL------LDN-----PAPSH 285

  Fly   121 SVEYIY----FQPSNFRNDIALLYMKRRYWSDFGNGLQYAQLPPHGMKPDQNESCRIIGYGATHH 181
            .||.|.    ::|....|||||  ||......|...:|...||.........:.|...|:|||..
Human   286 LVEKIVYHSKYKPKRLGNDIAL--MKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATED 348

  Fly   182 -AGPCQKRLFEAEVRVIDNQKC--RDIIGHIWAPQNGANTVCA--LGNNQDSCQGDSGGPLICTY 241
             ||.....|..|.|.:|.|:.|  ||:.|.|.:|    :.:||  |....|||||||||||:|..
Human   349 GAGDASPVLNHAAVPLISNKICNHRDVYGGIISP----SMLCAGYLTGGVDSCQGDSGGPLVCQE 409

  Fly   242 GGKDYIYGLVSHGLTCGIPGMPSIYTVTRPYYDWVQLLMQ 281
            .....:.|..|.|:.|.....|.:||....:.||:...|:
Human   410 RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQME 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34290	NP_001097899.2	Tryp_SPc	34..277	CDD:238113	84/261 (32%)
TMPRSS3	NP_076927.1	LDLa	74..107	CDD:238060
		SRCR_2	112..210	CDD:464747	6/25 (24%)
		Tryp_SPc	216..444	CDD:214473	83/261 (32%)