Protein Alignment CG34290 and PRSS2

DIOPT Version :10

• Sequence 1: NP_001097899.2
• Gene: CG34290 / 5740609
• FlyBaseID: FBgn0085319
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 80/289 - (27%)
• Similarity: 121/289 - (41%)
• Gaps: 63/289 - (21%)

  Fly    17 LHSLFIISVLESCHAVP------IVGGRIVSTVGSSTSKYPFMVSLQDVITRNTTNGVSYQHFCG 75
            ::.|.|::.:.:..|.|      ||||.|     ...:..|:.|||.           |..||||
Human     1 MNLLLILTFVAAAVAAPFDDDDKIVGGYI-----CEENSVPYQVSLN-----------SGYHFCG 49

  Fly    76 GSLISDRWILSAAHCVWRKNI-----------HYIAAFIGYENIENIGQLQPYGLESVEYIYFQP 129
            |||||::|::||.|| ::..|           |.|...:|..|||.:...:.: :.:.:.|....
Human    50 GSLISEQWVVSAGHC-YKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQF-INAAKIIRHPK 112

  Fly   130 SNFR---NDIALLYMKRRYWSDFGNGLQYAQLPPHGMKPDQNESCRIIGYGATHHAG---PCQKR 188
            .|.|   |||.|:.:...  :...:.:....||.  ..|.......|.|:|.|..:|   |.:.:
Human   113 YNSRTLDNDILLIKLSSP--AVINSRVSAISLPT--APPAAGTESLISGWGNTLSSGADYPDELQ 173

  Fly   189 LFEAEVRVIDNQKCRDIIGHIWAPQNGA---NTVCA--LGNNQDSCQGDSGGPLICTYGGKDYIY 248
            ..:|.  |:...:|.       |...|.   |..|.  |...:||||||||||::    ....:.
Human   174 CLDAP--VLSQAECE-------ASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVV----SNGELQ 225

  Fly   249 GLVSHGLTCGIPGMPSIYTVTRPYYDWVQ 277
            |:||.|..|.....|.:||....|.||::
Human   226 GIVSWGYGCAQKNRPGVYTKVYNYVDWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34290	NP_001097899.2	Tryp_SPc	34..277	CDD:238113	76/264 (29%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	76/266 (29%)