Protein Alignment CG34290 and KLK2

DIOPT Version :10

• Sequence 1: NP_001097899.2
• Gene: CG34290 / 5740609
• FlyBaseID: FBgn0085319
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 64/267 - (23%)
• Similarity: 115/267 - (43%)
• Gaps: 49/267 - (18%)

  Fly    31 AVPIVGGRIVSTVGSSTSKYPFMVSLQDVITRNTTNGVSYQH---FCGGSLISDRWILSAAHCVW 92
            |||::..|||..........|:.|::             |.|   .|||.|:..:|:|:||||:
Human    17 AVPLIQSRIVGGWECEKHSQPWQVAV-------------YSHGWAHCGGVLVHPQWVLTAAHCL- 67

  Fly    93 RKNIHYIAAFIGYENI---ENIGQLQP---------YGLESVEYIYFQP-SNFRNDIALLYMKRR 144
            :||..   .::|..|:   |:.||..|         |.:..:::...:| .:..:|:.||.:...
Human    68 KKNSQ---VWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEP 129

  Fly   145 YWSDFGNGLQYAQLPPHGMKPDQNESCRIIGYGATHHAGPCQKRLFE-AEVRVIDNQKCRDIIGH 208
              :...:.::...||.  .:|....:|...|:|:.......:.|..: ..:.::.|..|    ..
Human   130 --AKITDVVKVLGLPT--QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC----AR 186

  Fly   209 IWAPQNGANTVCA--LGNNQDSCQGDSGGPLICTYGGKDYIYGLVSHG-LTCGIPGMPSIYTVTR 270
            .::.:.....:||  ....:|:|.|||||||:|    ...:.|:.|.| ..|.:|..|::||...
Human   187 AYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVV 247

  Fly   271 PYYDWVQ 277
            .|..|::
Human   248 HYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34290	NP_001097899.2	Tryp_SPc	34..277	CDD:238113	61/262 (23%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	60/259 (23%)