Protein Alignment ATbp and PLAGL2

DIOPT Version :10

• Sequence 1: NP_001104481.2
• Gene: ATbp / 5740592
• FlyBaseID: FBgn0039946
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_002648.1
• Gene: PLAGL2 / 5326
• HGNCID: 9047
• Length: 496
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 63/274 - (22%)
• Similarity: 95/274 - (34%)
• Gaps: 85/274 - (31%)

  Fly   160 QQLQQQRDVAKELA------ELHANAVAAAAASAAVVSTGEGTTQSNSAIDIKIEPSSLTLTPEM 218
            |..:|:.:|..:|.      |..:........|....|.||           |:.|.||. .||.
Human    13 QDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGE-----------KLRPHSLP-QPEQ 65

  Fly   219 QAAAAAGGTIYHLPQLVPPPVPPPPPGSGFVSV------SASTSTS------------------- 258
            :.        |..|||        ..|..|.|.      .|:.|..
Human    66 RP--------YSCPQL--------HCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLR 114

  Fly   259 NTVSTTPPNVLQQQQQLNMSVVP---STAMA----AAMLAASQEQLP-----KDSNSTTA----- 306
            |.:.|..||    ::.|:.|...   :|.:.    .||.|||...|.     :...||.|
Human   115 NHLQTHDPN----KEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHL 175

  Fly   307 -SAGSAVSSDDGERWYVCDYETCGLKFKYKSRMELHRVVHSKERRFNCELCSASFKQSCNLSTHR 370
             :....|:....|:.:.||:  |..:|..:..:..|.|||:..:.|.|:.|:..|.:..:|:.|.
Human   176 KAHSRRVAGGAKEKKHPCDH--CDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHV 238

  Fly   371 KKKHA--LRGIKSE 382
            ||.|:  |..||:|
Human   239 KKSHSQELLKIKTE 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATbp	NP_001104481.2	C2H2 Zn finger	323..345	CDD:275368	6/21 (29%)
		C2H2 Zn finger	353..371	CDD:275368	5/17 (29%)
PLAGL2	NP_002648.1	C2H2 Zn finger	70..92	CDD:275368	7/29 (24%)
		zf-H2C2_2	85..107	CDD:463886	2/21 (10%)
		zf-C2H2	98..120	CDD:395048	1/21 (5%)
		C2H2 Zn finger	100..120	CDD:275368	1/19 (5%)
		C2H2 Zn finger	129..149	CDD:275368	3/19 (16%)
		C2H2 Zn finger	158..178	CDD:275368	3/19 (16%)
		C2H2 Zn finger	193..213	CDD:275368	6/21 (29%)
		C2H2 Zn finger	221..239	CDD:275368	5/17 (29%)