DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and DIP-epsilon

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	111/431 - (25%)
Similarity:	179/431 - (41%)	Gaps:	68/431 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 SAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAWK--RGIAILTAGSVKVTPDPR 138
            |..:.:...:|.|....|......|..:.|.|.|.|..:|.|||.  ...||||..:..:|.:||
  Fly    42 STLNNVISEDPEFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPR 106

  Fly   139 VRLVNG-------FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVK 196
            :.:.:.       :.|.|.:....|.|.|:|||.|:..:.....|:::|||.|....|...:.|:
  Fly   107 ISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVR 171

  Fly   197 KGSSVRIECSATGNPMPNVTWSRK--NNILPNGEEKLH---SHVLSIENVDRHKGGVYICTANNR 256
            :|.:|.:.|.|.|:|.|.:.|.|.  |.|:.|...::|   :..|.:|.:.|...|.|:|.|:|.
  Fly   172 EGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNG 236

  Fly   257 VGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDTMQLDT-TERHI 320
            |....|.::.:.|.|||.:.:...:|....|...||.|.:.........|.::..|:.| :.::.
  Fly   237 VPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYK 301

  Fly   321 METRGSRHT------LIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKD 379
            .||.....:      |.|..|...|:|||.|||:|..|.....::|       ..:|||.:|...
  Fly   302 TETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKL-------YMSSPPTTQPPP 359

  Fly   380 -----RYNISWAVD------SHSPIEEYKLSFRKLPQGHEVVGNAI----DSSSSSSSMSSSSSQ 429
                 |...:.|.:      .::|:.                ||.|    :..::|...|..||.
  Fly   360 TTTTLRRTTTTAAEIALDGYINTPLN----------------GNGIGIVGEGPTNSVIASGKSSI 408

  Fly   430 MYGSGLHAHRIGSNMGGLSGLSGSG-------SYSGYGNVI 463
            .|.|.|  :.|..:...|:|.|..|       |...:||::
  Fly   409 KYLSNL--NEIDKSKQKLTGSSPKGFDWSKGKSSGSHGNLM 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	26/88 (30%)
		Ig	103..177	CDD:143165	24/82 (29%)
		IG_like	191..269	CDD:214653	24/82 (29%)
		IGc2	198..258	CDD:197706	21/64 (33%)
		I-set	273..360	CDD:254352	23/93 (25%)
		Ig	290..359	CDD:143165	20/75 (27%)
		FN3	<466..524	CDD:238020
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	27/95 (28%)
		Ig	69..139	CDD:143165	21/69 (30%)
		IG_like	165..249	CDD:214653	24/83 (29%)
		IGc2	172..237	CDD:197706	21/64 (33%)
		IG_like	267..348	CDD:214653	22/87 (25%)
		Ig	270..339	CDD:299845	19/68 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810