DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34353 and iglon5

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	314	Identity:	88/314 - (28%)
Similarity:	141/314 - (44%)	Gaps:	31/314 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LPHILFLAIAVVSLHFESVS-AQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAWK 120
            |.|.|.|.:|::   ::..| ||:....:.|      :....:.||::||.|::....|: .||.
Zfish     6 LRHALALLLALL---WKGPSGAQAAEFGHLP------DNITVLEGESVVLRCKIDEEVTH-KAWL 60

  Fly   121 RGIAILTAGSVKVTPDPRVRLVNG----FNLQIRDALPTDAGDYICQIATMDPREITHTVEIL-V 180
            ....||..|:.|.:.|.||.|.|.    |:::|...:..|.|.|.|.....:.....|...|: |
Zfish    61 NRSNILFTGTDKWSLDSRVSLENNNNSDFSIRIERVMVADEGPYTCSFQARNKPRTAHVYLIVQV 125

  Fly   181 PPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSR-KNNILPNGEEKLHSHVLSIENVDRH 244
            |.||.:||.  ...|.:|..|.:.|.|.|.|.|.:||.. |..:|..||      .|.|..:.||
Zfish   126 PARIVNISQ--DKSVNEGEDVNLFCLAVGRPEPTITWKDFKYGLLNEGE------FLEITEIKRH 182

  Fly   245 KGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKD 309
            :...:.|..||.|..|.:.:|.:.|.:.|.|:..:.:. :..|..|.|.|...........|::|
Zfish   183 QAEDFECITNNGVAPPDTRKVKVTVNYPPIITDVKNMP-AQVGKTAILRCEAMAVPTASFEWYRD 246

  Fly   310 ---TMQLDTTERHIMETRGSRHTLIIRKVHPQDFGNYSCVAENQLGKARKTLQL 360
               .::.|.|.:  ::...:|..|:...|..:.||||:|.|.|:||.:..::.|
Zfish   247 DRRPVESDNTLK--IKNEKTRSLLLFTNVTEKHFGNYTCFASNRLGASNASMLL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	25/84 (30%)
		Ig	103..177	CDD:143165	22/77 (29%)
		IG_like	191..269	CDD:214653	24/78 (31%)
		IGc2	198..258	CDD:197706	20/60 (33%)
		I-set	273..360	CDD:254352	22/89 (25%)
		Ig	290..359	CDD:143165	19/71 (27%)
		FN3	<466..524	CDD:238020
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	25/96 (26%)
		Ig	35..123	CDD:299845	24/88 (27%)
		Ig	125..>183	CDD:299845	23/65 (35%)
		I-set	128..207	CDD:254352	28/86 (33%)
		IG_like	217..298	CDD:214653	20/83 (24%)
		ig	223..296	CDD:278476	20/74 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4772
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.960