DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34353 and Ntm

DIOPT Version :9

Sequence 1:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:336 Identity:99/336 - (29%)
Similarity:154/336 - (45%) Gaps:43/336 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 RTISKPGHIRDRRVGSLPHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVL 105
            :||....|      .|:...:|..:|.:.| |:.|..:|    .:..|....:......||:..|
  Rat     2 KTIQAKMH------NSISWAIFTGLAALCL-FQGVPVRS----GDATFPKAMDNVTVRQGESATL 55

  Fly   106 PCEVANTDTYVVAWKRGIAILTAGSVKVTPDPRVRLVNG----FNLQIRDALPTDAGDYICQIAT 166
            .|.:.|..|. |||.....||.||:.|...||||.|::.    ::::|::....|.|.|.|.:.|
  Rat    56 RCTIDNRVTR-VAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQT 119

  Fly   167 MDPREITHTVEIL--VPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNNILPN--- 226
             |....|..|.::  |.|:|..||:  .:.:.:|:::.:.|.|||.|.|.|||   .:|.|.   
  Rat   120 -DNHPKTSRVHLIVQVSPKIVEISS--DISINEGNNISLTCIATGRPEPTVTW---RHISPKAVG 178

  Fly   227 --GEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVER----PVVFSG 285
              .|::    .|.|:.:.|.:.|.|.|:|:|.|..|...:|.:.|.:.|.||..:    ||    
  Rat   179 FVSEDE----YLEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPV---- 235

  Fly   286 EGHEATLVCIVHGETQPEVIWFKDTMQLDTTERHI-METRGSRHTLIIRKVHPQDFGNYSCVAEN 349
             |.:.||.|........|..||||..:|...::.: :|.|.....|....|...|:|||:|||.|
  Rat   236 -GQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSRLTFFNVSEHDYGNYTCVASN 299

  Fly   350 QLGKARKTLQL 360
            :||....::.|
  Rat   300 KLGHTNASIML 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 28/85 (33%)
Ig 103..177 CDD:143165 25/77 (32%)
IG_like 191..269 CDD:214653 24/82 (29%)
IGc2 198..258 CDD:197706 21/64 (33%)
I-set 273..360 CDD:254352 29/91 (32%)
Ig 290..359 CDD:143165 23/69 (33%)
FN3 <466..524 CDD:238020
NtmXP_017451354.1 Ig 44..132 CDD:416386 28/89 (31%)
Ig strand A' 44..49 CDD:409353 0/4 (0%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 4/6 (67%)
Ig strand C 64..70 CDD:409353 4/6 (67%)
CDR2 71..83 CDD:409353 5/11 (45%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 10/33 (30%)
Ig strand D 87..94 CDD:409353 3/6 (50%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/4 (50%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 136..205 CDD:404760 24/77 (31%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 1/8 (13%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 29/88 (33%)
putative Ig strand A 223..229 CDD:409353 3/5 (60%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 1/3 (33%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.910

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