DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34353 and NTM

DIOPT Version :9

Sequence 1:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:328 Identity:97/328 - (29%)
Similarity:154/328 - (46%) Gaps:37/328 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 IRDRRVGSLPHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTD 113
            |:.:...|:...:|..:|.:.| |:.|..:|    .:..|....:......||:..|.|.:.|..
Human     4 IQPKMHNSISWAIFTGLAALCL-FQGVPVRS----GDATFPKAMDNVTVRQGESATLRCTIDNRV 63

  Fly   114 TYVVAWKRGIAILTAGSVKVTPDPRVRLVNG----FNLQIRDALPTDAGDYICQIATMDPREITH 174
            |. |||.....||.||:.|...||||.|::.    ::::|::....|.|.|.|.:.| |....|.
Human    64 TR-VAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQT-DNHPKTS 126

  Fly   175 TVEIL--VPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNNILPN-----GEEKLH 232
            .|.::  |.|:|..||:  .:.:.:|:::.:.|.|||.|.|.|||   .:|.|.     .|::  
Human   127 RVHLIVQVSPKIVEISS--DISINEGNNISLTCIATGRPEPTVTW---RHISPKAVGFVSEDE-- 184

  Fly   233 SHVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVER----PVVFSGEGHEATLV 293
              .|.|:.:.|.:.|.|.|:|:|.|..|...:|.:.|.:.|.||..:    ||     |.:.||.
Human   185 --YLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-----GQKGTLQ 242

  Fly   294 CIVHGETQPEVIWFKDTMQLDTTERHI-METRGSRHTLIIRKVHPQDFGNYSCVAENQLGKARKT 357
            |........|..|:||..:|...::.: :|.|.....||...|...|:|||:|||.|:||....:
Human   243 CEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNAS 307

  Fly   358 LQL 360
            :.|
Human   308 IML 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 28/85 (33%)
Ig 103..177 CDD:143165 25/77 (32%)
IG_like 191..269 CDD:214653 24/82 (29%)
IGc2 198..258 CDD:197706 21/64 (33%)
I-set 273..360 CDD:254352 29/91 (32%)
Ig 290..359 CDD:143165 23/69 (33%)
FN3 <466..524 CDD:238020
NTMNP_001338930.1 Ig 44..132 CDD:416386 28/89 (31%)
Ig strand A' 44..49 CDD:409353 0/4 (0%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 4/6 (67%)
Ig strand C 64..70 CDD:409353 4/6 (67%)
CDR2 71..83 CDD:409353 5/11 (45%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 10/33 (30%)
Ig strand D 87..94 CDD:409353 3/6 (50%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/4 (50%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 136..205 CDD:404760 24/77 (31%)
Ig strand A' 142..147 CDD:409353 1/6 (17%)
Ig strand B 153..160 CDD:409353 1/6 (17%)
Ig strand C 166..171 CDD:409353 3/7 (43%)
Ig strand D 177..180 CDD:409353 0/2 (0%)
Ig strand E 184..190 CDD:409353 2/9 (22%)
Ig strand F 197..204 CDD:409353 3/6 (50%)
Ig strand G 211..219 CDD:409353 1/7 (14%)
Ig_3 222..299 CDD:404760 26/81 (32%)
putative Ig strand A 223..229 CDD:409353 3/5 (60%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 1/3 (33%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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