DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and dpr12

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	69/285 - (24%)
Similarity:	111/285 - (38%)	Gaps:	79/285 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 ISKPGHIRDRRVGSLPHILFLAIAVVSLHFESVSAQSMMTKNE---------------------- 85
            :.:|.|:.:.|:    .:|.|...:::...|. ..:|::|.|:
  Fly    12 LRRPLHLMELRI----LLLCLPTLLLATTLEP-DQKSILTDNDWKKLWMRGGINGDSKLDNNLDS 71

  Fly    86 ---PMFISRSETFKFIT----GETIVLPCEVANTDTYVVAW-------KRGIAILTAGSVKVTPD 136
               ||| ..||.....|    |.|..|.|:|:..|...|.|       :|...||::|:...|.|
  Fly    72 SDSPMF-EDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTND 135

  Fly   137 PRVRLV-----NGFNLQIRDALPTDAGDYICQIATMDPRE-ITHTV--EILVPPRIHHISTGGHL 193
            .|..::     |.:.|||:.....|.|.|.||::|  |.. |:|.|  :::||...  |...|.|
  Fly   136 ERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVST--PTGIISHFVNLQVVVPEAF--ILGSGEL 196

  Fly   194 QVKKGSSVRIECSATGNPMP--NVTWSRKNNIL----------------PNGEEKLHSHVLSIEN 240
            .|..||::.:.|....:|.|  .|.|.:.:.::                |..:.:     |.|..
  Fly   197 HVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSR-----LIIRE 256

  Fly   241 VDRHKGGVYICTANNRVGQPASSQV 265
            ......|.|.|:|:|.  :|||..|
  Fly   257 PQVTDSGNYTCSASNT--EPASIYV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	29/94 (31%)
		Ig	103..177	CDD:143165	27/88 (31%)
		IG_like	191..269	CDD:214653	22/93 (24%)
		IGc2	198..258	CDD:197706	15/77 (19%)
		I-set	273..360	CDD:254352
		Ig	290..359	CDD:143165
		FN3	<466..524	CDD:238020
dpr12	NP_652462.3	IG	86..183	CDD:214652	30/98 (31%)
		Ig_3	193..271	CDD:404760	17/82 (21%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/8 (13%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810