Protein Alignment CG34353 and klg

DIOPT Version :9

• Sequence 1: NP_001287571.1
• Gene: CG34353 / 5740590
• FlyBaseID: FBgn0085382
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_524454.2
• Gene: klg / 42707
• FlyBaseID: FBgn0017590
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 199/583 - (34%)
• Similarity: 307/583 - (52%)
• Gaps: 100/583 - (17%)

  Fly     9 RSSSSSSRIAYKFEC--------------HSNSKQNSKTGKMAAEARTISKPGHIRDRRVGSLPH 59
            :||...:|...:..|              |:.|      |..|.||...::..:.|     |:.:
  Fly    32 KSSQRRNRAPLQMNCPILIVISLGWLLHAHAGS------GGFAVEAAISNRGSNSR-----SMSN 85

  Fly    60 ILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAWKRGIA 124
            :.           :|..|.|.:|...|.|:||..|::.:.|:|:||||:|.|...:|:.|:||..
  Fly    86 VQ-----------QSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVENLGNFVLLWRRGTN 139

  Fly   125 ILTAGSVKVTPDPRVRLVNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHIST 189
            :|||.::.||.|.||||::|:||:|.|..|.|||||:|||:....|:..|||||||||.:..|.|
  Fly   140 VLTASNIMVTRDERVRLIDGYNLEISDLEPQDAGDYVCQISDKINRDQVHTVEILVPPSVRAIPT 204

  Fly   190 GGHLQVKKGSSVRIECSATGNPMPNVTWSRKNNILPNGEEKLHSHVLSIENVDRHKGGVYICTAN 254
            .|.||.:||..:.:||..:|||:|::.|::|:....:........:|::|.::|.:.|||.|||:
  Fly   205 SGQLQARKGGPITLECKGSGNPVPSIYWTKKSGANKSTARIGDGPILTLEKLERQQAGVYQCTAD 269

  Fly   255 NRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDTMQLDTTERH 319
            |.||.|.:..:.|.||:.|:|.||:..:.||||.||.|||||..:....|.|::::..:.:|:|.
  Fly   270 NGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRR 334

  Fly   320 IMETRGSRHTLIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKDRYNIS 384
            ||.||.:||.|.||.:..:|||||||||:|.||::||.::|||:|..|.|.||...:..|.||::
  Fly   335 IMATRANRHMLTIRHIQQEDFGNYSCVADNSLGRSRKYMELSGRPGAAEFYSPKWGRSPDSYNLT 399

  Fly   385 WAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGSNMGGLSG 449
            |.:||:.|:||.:|.:|::                         ||
  Fly   400 WKIDSYPPLEEVRLLYRRV-------------------------QM------------------- 420

  Fly   450 LSGSGSYSGYGNVIHWGHNDWRNVVLPAV--PVSHHYAQGMSYMVRGLDPDQHYEATVQSRNRYG 512
               :.:|...|.        |.:.:|...  |.|......|||.::.|.|..:|||.||::||||
  Fly   421 ---NETYQQPGR--------WHDFILTPEHRPASEPLTHIMSYTIKNLHPGGYYEAIVQAKNRYG 474

  Fly   513 WSDLTN--SFVFSTSSND-GPVDLSTFLNHGLSDNEMRDLSV-TFYGSSAINRQKLGLLALSS 571
            |:::::  .||.:|:|.| ||.|.....:   |.:.....|: :..||:.::...|..||||:
  Fly   475 WNEVSDIFQFVVATNSQDIGPEDAEVVAS---SKSRSNSASIGSLPGSTVLHTALLLALALSN 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	42/79 (53%)
		Ig	103..177	CDD:143165	37/73 (51%)
		IG_like	191..269	CDD:214653	27/77 (35%)
		IGc2	198..258	CDD:197706	19/59 (32%)
		I-set	273..360	CDD:254352	42/86 (49%)
		Ig	290..359	CDD:143165	33/68 (49%)
		FN3	<466..524	CDD:238020	21/61 (34%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	22/82 (27%)
		IG_like	109..195	CDD:214653	43/85 (51%)
		Ig	118..191	CDD:143165	36/72 (50%)
		IG_like	205..274	CDD:214653	24/68 (35%)
		IGc2	213..273	CDD:197706	19/59 (32%)
		IGc2	301..367	CDD:197706	32/65 (49%)
		FN3	392..486	CDD:238020	35/148 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I6839
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4772
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D27331at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14108
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45080
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	8	7.970