DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and Ama

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	91/327 - (27%)
Similarity:	151/327 - (46%)	Gaps:	27/327 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAWKR- 121
            |.:..|.:.:..:...::|..|::  :.|:....|:......|:::...|.|.......|:|.:
  Fly     7 PDMARLRLLIGLIFCLAISLDSVL--SAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKR 69

  Fly   122 ------GIAILTAGSVKVTPDPR--VRLVNG-------FNLQIRDALPTDAGDYICQIATMDPRE 171
                  ...:|:..::...||.|  |.:..|       :..:|::...:|.|.|.||:......:
  Fly    70 PSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEK 134

  Fly   172 ITH--TVEILVPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNN-ILPNGEEKLHS 233
            :|.  :::|..||.|.. :|.....|.:|.::.:.|.|.|.|.|.::|:|::| ::|.|...|..
  Fly   135 VTKKLSLQIKTPPVIAE-NTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAE 198

  Fly   234 HVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHG 298
            ..|.|.:|.|...|.|.|.|.|..|||....:.:.|.|.|:|:|:||.:.....|.|.|.|.|.|
  Fly   199 PTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQG 263

  Fly   299 ETQPEVIWFKDTMQLDTTERH-IMETRGSRHT----LIIRKVHPQDFGNYSCVAENQLGKARKTL 358
            ...|.|:|.|:.:.|.::..| :..|..|..|    |.|..|..:|||:|.|.|.|:||.|...|
  Fly   264 YPAPTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARL 328

  Fly   359 QL 360
            .|
  Fly   329 HL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	19/97 (20%)
		Ig	103..177	CDD:143165	17/91 (19%)
		IG_like	191..269	CDD:214653	25/78 (32%)
		IGc2	198..258	CDD:197706	21/60 (35%)
		I-set	273..360	CDD:254352	34/91 (37%)
		Ig	290..359	CDD:143165	27/73 (37%)
		FN3	<466..524	CDD:238020
Ama	NP_731114.2	I-set	33..143	CDD:254352	20/109 (18%)
		Ig	37..127	CDD:299845	17/89 (19%)
		IG_like	154..234	CDD:214653	25/79 (32%)
		IGc2	161..223	CDD:197706	21/61 (34%)
		I-set	254..330	CDD:254352	28/75 (37%)
		IGc2	254..322	CDD:197706	24/67 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810