DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and dpr10

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	96/468 - (20%)
Similarity:	159/468 - (33%)	Gaps:	142/468 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IAYKFECHSNSKQNSKTGKMAAEAR-TISKPGHIRDRRVGSLPHILFLAIAVVSLHFESVSAQSM 80
            :.|:.:..||:..|:      |||: |.:.|.|        .||                    .
  Fly    17 VCYQRQSVSNNNHNN------AEAKPTHAPPSH--------YPH--------------------G 47

  Fly    81 MTKNEPMF-ISRSETFKFITGETIVLPCEVANTDTYVVAW--KRGIAILTAGSVKVTPDPRV--- 139
            ...|||.| ::.......:.|::..|.|.|.:.....|||  .|.:.|||.|:...|.|.|.
  Fly    48 HKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTS 112

  Fly   140 --RLVNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVR 202
              |.::.:.|||:.|...|||.|.|||:|...|..:..:.|:
  Fly   113 YHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIV----------------------- 154

  Fly   203 IECSATGNPMPNVTWSRKNNILPNGEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQVVL 267
                                      :.:.:....|.....:....||  |.|||.|.::.:..
  Fly   155 --------------------------DLIDAETSDIMQQYYNDDAFYI--AENRVYQSSNDEFA- 190

  Fly   268 HVLFSP--EISVERPVVFSG------EGHEATLVCIVHGETQP--EVIWF-KDTMQLDTTE--RH 319
             .:|.|  .::|....:..|      :|....|.||:....:|  .:.|: :|.:..:.|.  |.
  Fly   191 -GMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRL 254

  Fly   320 IMETRGSRHTLIIRKVHPQDF---GNYSCVAEN-QLGKARKTLQLSGKPNVAVFNSPPISQYKDR 380
            ..:|..|..|..|..::..|.   |.|||...| ::...|..:....:|.....|:.|.:
  Fly   255 KFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAA----- 314

  Fly   381 YNISWAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGSNMG 445
              ::.|.        :...|.:..|...|:...:   ::...:.:.||.:..||          |
  Fly   315 --VALAC--------WSCHFGQATQAVRVISTMV---AALVLLEACSSLLLQSG----------G 356

  Fly   446 GLSGLSGSGSYSG 458
            | .|..|.||.:|
  Fly   357 G-GGCPGGGSPAG 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	30/86 (35%)
		Ig	103..177	CDD:143165	28/80 (35%)
		IG_like	191..269	CDD:214653	8/77 (10%)
		IGc2	198..258	CDD:197706	6/59 (10%)
		I-set	273..360	CDD:254352	23/103 (22%)
		Ig	290..359	CDD:143165	19/77 (25%)
		FN3	<466..524	CDD:238020
dpr10	NP_729591.1	Ig	63..143	CDD:299845	28/79 (35%)
		IG_like	210..297	CDD:214653	20/86 (23%)
		IGc2	217..287	CDD:197706	18/69 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810