DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and ImpL2

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	68/299 - (22%)
Similarity:	111/299 - (37%)	Gaps:	104/299 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ANTDTYVVAWKRGIAILTAGSVKVTPDPRVRLVNGFN-----LQIRDALPTD---AGDYICQIAT 166
            |..:.:|.|    :|:|..||:.......|.||:..|     ::..:..|.:   ..|::
  Fly     3 AKMNLHVCA----LALLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWL----- 58

  Fly   167 MDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNNILPNGE-EK 230
                :.|.|     ||.        .||...|:::.|.|...|:.:|::.|...:  ||..| :.
  Fly    59 ----KFTKT-----PPT--------KLQQADGATIEIVCEMMGSQVPSIQWVVGH--LPRSELDD 104

  Fly   231 LHS---------------------HVLSIENVDRHKGGVYICT---------ANNRVGQPASSQV 265
            |.|                     ||||       :...|.|.         |:..|..|.||::
  Fly   105 LDSNQVAEEAPSAIVRVRSSHIIDHVLS-------EARTYTCVGRTGSKTIYASTVVHPPRSSRL 162

  Fly   266 VLHVLFSPEIS---VERPVVFSGE-------GHEATLVCIVHGETQPEVIWFKDTMQLDTTERHI 320
                  :||.:   .::|.:...|       |....|.|.||...:.|:.|      |:...:.|
  Fly   163 ------TPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITW------LNNENKEI 215

  Fly   321 METRGSRH------TLIIRKVHPQDFGNYSCVAENQLGK 353
            ::  |.||      .|:|.::..:|.|||.|:|.|.:||
  Fly   216 VQ--GHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	15/77 (19%)
		Ig	103..177	CDD:143165	15/74 (20%)
		IG_like	191..269	CDD:214653	24/108 (22%)
		IGc2	198..258	CDD:197706	18/90 (20%)
		I-set	273..360	CDD:254352	27/97 (28%)
		Ig	290..359	CDD:143165	22/70 (31%)
		FN3	<466..524	CDD:238020
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	21/71 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900