DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34353 and CG13506

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	113/531 - (21%)
Similarity:	208/531 - (39%)	Gaps:	119/531 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 MTKNE------PMFISRSETFKFITGETIVLPCEVANTD-TYVVAWKRGIAILTAGSVKVTPDPR 138
            :|||.      |.|.......:...|:.::|.|:..|.. :..|.|.:...|:..|...::  .|
  Fly    59 VTKNHAEQEAPPYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQNPIS--QR 121

  Fly   139 VRLVNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQV-------- 195
            |:.:...::.:|:..|.|:.||.|:|.....|:  ||.          :..|..|.:
  Fly   122 VQCMLNNSILLRNVSPEDSDDYYCEILPQRVRQ--HTA----------LRVGARLSILCDDRDIT 174

  Fly   196 ------KKGSSVRIECSATGNPMPNVTWSRKN-NILPNGEEKLHSHVLSIENVDRHKGGVYICTA 253
                  ::|...::||.........:.||..: |..|:..:. .:.|:.::|||....|.|.|.|
  Fly   175 DRSQTFRQGDHHKLECRTYLPDNATIKWSFNDLNGQPSSVDN-QNGVIILDNVDEKNAGDYQCLA 238

  Fly   254 NNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDTMQLDTTER 318
            ::....|....|.:.|.:||.:|..|..|.:.:|..|.|.|....:......:.||...|..:::
  Fly   239 DDGSRHPPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDK 303

  Fly   319 HIME----TRGSRHTLIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKD 379
            :.::    ...:|.|||:|:|...|.|.|.|..||.:|        |.:..|.|..:|...|::|
  Fly   304 YSLKDSVHNDHNRTTLIVREVTDSDLGEYLCQVENAIG--------SNEVKVHVSYNPETPQFED 360

  Fly   380 RYNISWAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGSNM 444
                       ..:|..|::...|.:.|:::..|:.....:.|.:.|:.|:    |..||
  Fly   361 -----------MTVEGNKVTLHWLVRSHQLLSEAMLDYQLTGSYTWSTVQV----LETHR----- 405

  Fly   445 GGLSGLSGSGSYSGYGNVIHWGHNDWRNVVLPAVPVSHHYAQGMSYMVRGLDPDQHYEATVQSRN 509
                                  ||:..|:    ..::|...     :.||:     :.|.|:::|
  Fly   406 ----------------------HNNTDNI----WKITHQLE-----LSRGV-----WHARVKTKN 434

  Fly   510 RYGWSDLTNSFVF-----STSSNDGPVDL--STFLNHGLSDNEMRDLSVTFYGSSAINRQKLGLL 567
            ..|||..:|..||     |....|..|:|  ...:..|:       :.::...:|::.|..:|::
  Fly   435 TKGWSHFSNDHVFEIPEDSEVDKDEEVELPPDEIVQAGI-------MPMSKGAASSMQRLNVGVI 492

  Fly   568 ALSSATLALSL 578
            .|::..|.:.|
  Fly   493 LLAALLLRVRL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	20/80 (25%)
		Ig	103..177	CDD:143165	19/74 (26%)
		IG_like	191..269	CDD:214653	18/92 (20%)
		IGc2	198..258	CDD:197706	15/60 (25%)
		I-set	273..360	CDD:254352	24/90 (27%)
		Ig	290..359	CDD:143165	19/72 (26%)
		FN3	<466..524	CDD:238020	15/62 (24%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	15/68 (22%)
		IGc2	83..146	CDD:197706	15/64 (23%)
		IG_like	176..254	CDD:214653	17/78 (22%)
		Ig	176..239	CDD:299845	14/63 (22%)
		I-set	258..349	CDD:254352	26/98 (27%)
		Ig	275..348	CDD:143165	20/80 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45080
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910