DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34353 and Fgfrl1

DIOPT Version :9

Sequence 1:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_954545.1 Gene:Fgfrl1 / 360903 RGDID:735156 Length:529 Species:Rattus norvegicus


Alignment Length:470 Identity:96/470 - (20%)
Similarity:171/470 - (36%) Gaps:100/470 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 PHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAW-KR 121
            |.:|.|.:..:.....:.....|..|..|..::|       .|.|:.|.|.|......:..| |.
  Rat     5 PALLLLLLGALPSAEAARGPPRMADKVVPRQVAR-------LGRTVRLQCPVEGDPPPLTMWTKD 62

  Fly   122 GIAILTAGS-VKVTPDPRVRLVNGFNLQIRDALPTDAGDYICQIAT-MDPREITHTVEIL--VPP 182
            |..|.:..| .:|.|.         .|::::....|||.|:|:... .....:.:|:.|:  :.|
  Rat    63 GRTIHSGWSRFRVLPQ---------GLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDISP 118

  Fly   183 RIHHISTGG-----------------HLQVKK----------GSSVRIECSATGNPMPNVTWSRK 220
            ...:...||                 ..|..|          |||||::|.|:|:|.|::.|.:.
  Rat   119 GKENPGPGGSSGGQEDPVSQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKD 183

  Fly   221 NNILPNGEEKLH---SHVLSIENVDRHKGGVYICTANNRVGQPASS---QVVLHVLFSPEISVER 279
            :..|...|...|   ...||::|:.....|.|.|..:||.|...::   .|:......|.::...
  Rat   184 DQTLTRLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTH 248

  Fly   280 PVVFSGE-GHEATLVCIVHGETQPEVIWFKDTMQLDTTERH--IMETRGSR-------------- 327
            ||..:.: |...:..|.|..:.:|.:.|.| .::..:..||  .::..|.:              
  Rat   249 PVNTTVDFGGTTSFQCKVRSDVKPVIQWLK-RVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPD 312

  Fly   328 ----HTLIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKDRYNISWAVD 388
                :.|:|.:....|.|.|.|:..|.:|.:.::..|:..|:... ..||::......::.|.|.
  Rat   313 GSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKP-PGPPVAHSSSTTSLPWPVV 376

  Fly   389 SHSP---------IEEYKLSFRKLP---------QGHEVVGNAIDSSSSSS--SMSSSSSQMYGS 433
            ...|         :..:....:|.|         .||...|.:.:.|....  |::....:.:||
  Rat   377 IGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPVPGHRPPGTSRERSGDKDLPSLAVGICEEHGS 441

  Fly   434 GLHAHRI---GSNMG 445
            .:....|   ||..|
  Rat   442 TMAPQHILAPGSTAG 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 20/84 (24%)
Ig 103..177 CDD:143165 17/76 (22%)
IG_like 191..269 CDD:214653 27/110 (25%)
IGc2 198..258 CDD:197706 22/62 (35%)
I-set 273..360 CDD:254352 20/107 (19%)
Ig 290..359 CDD:143165 16/88 (18%)
FN3 <466..524 CDD:238020
Fgfrl1NP_954545.1 I-set 29..112 CDD:400151 22/98 (22%)
Ig strand A' 35..38 CDD:409353 0/2 (0%)
Ig strand B 41..50 CDD:409353 3/8 (38%)
Ig strand C 56..61 CDD:409353 1/4 (25%)
Ig strand C' 64..67 CDD:409353 0/2 (0%)
Ig strand D 72..77 CDD:409353 1/4 (25%)
Ig strand E 78..84 CDD:409353 1/14 (7%)
Ig strand F 91..99 CDD:409353 3/7 (43%)
Ig strand G 102..112 CDD:409353 1/9 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 117..152 5/34 (15%)
IgI_2_FGFRL1-like 143..234 CDD:409442 25/90 (28%)
Ig strand B 164..168 CDD:409442 2/3 (67%)
Ig strand C 177..181 CDD:409442 0/3 (0%)
Ig strand E 200..204 CDD:409442 1/3 (33%)
Ig strand F 214..219 CDD:409442 2/4 (50%)
Ig strand G 227..230 CDD:409442 0/2 (0%)
Ig 242..350 CDD:416386 20/108 (19%)
Ig strand A 242..245 CDD:409353 1/2 (50%)
Ig strand A' 249..253 CDD:409353 2/3 (67%)
Ig strand B 261..268 CDD:409353 2/6 (33%)
Ig strand C 272..279 CDD:409353 3/7 (43%)
Ig strand D 304..309 CDD:409353 0/4 (0%)
Ig strand E 317..322 CDD:409353 1/4 (25%)
Ig strand F 330..338 CDD:409353 3/7 (43%)
Ig strand G 341..349 CDD:409353 1/7 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 405..427 4/21 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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