DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34353 and DIP-zeta

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	111/463 - (23%)
Similarity:	182/463 - (39%)	Gaps:	104/463 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 EPMFISRSETFKFITGETIVLPCEVANTDTYVVAWK--RGIAILTAGSVKVTPDPRVRLVNG--- 144
            ||.|....|......|..:.|.|.|.|..:|.|||.  ...||||..:..:|.:||:.:.:.
  Fly   112 EPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHD 176

  Fly   145 ----FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIEC 205
                :.|.|.:....|.|.|:|||.|:..:.....:.::|||.|....:...:.|::|:::.:.|
  Fly   177 RHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRC 241

  Fly   206 SATGNPMPNVTWSR---------KNNILPNGEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPA 261
            .|:|:|.|.:.|.|         ||:|:...|    ...|.|..:.|...|.|:|.|:|.|....
  Fly   242 RASGSPRPIIKWKRDDNSRIAINKNHIVNEWE----GDTLEITRISRLDMGAYLCIASNGVPPTV 302

  Fly   262 SSQVVLHVLFSPEISVERPVVFSGEGHEATLVC------------------IVHGETQPEVIWFK 308
            |.::.:.|.|.|.:.:...:|.:.||...|:.|                  |:|...:.:|   :
  Fly   303 SKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKV---E 364

  Fly   309 DTMQLDTTERHIMETRGSRHTLIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPP 373
            .|:.|...:.|:        .|.|..|...|.|.|.|||:|..|:....::|       ..:.||
  Fly   365 ATVGLPAYKTHM--------KLTIINVSSGDDGIYKCVAKNPRGETDGIIRL-------YVSYPP 414

  Fly   374 ISQYKDRYNISWAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAH 438
            .:.....|    :.|:|              .|.    |.|:::.:.....|:.| :|....:.
  Fly   415 TTASSGIY----STDTH--------------WGE----NGINNNYAYGGPDSTRS-IYAQDKNT- 455

  Fly   439 RIGSNMGGLSGLSGSGSY----------SGYGNVIH------WGHND-----WRNVVLPAVPVSH 482
            |..||:..: |||...|:          :|..|...      .|||.     |..||:..:.::.
  Fly   456 RYQSNLNEI-GLSEQKSFLDKTQNPLLANGNANEADAESNGARGHNPSMAIAWLFVVIATLLLTI 519

  Fly   483 HYAQGMSY 490
            ..|.|.|:
  Fly   520 RSAVGSSH 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	25/88 (28%)
		Ig	103..177	CDD:143165	24/82 (29%)
		IG_like	191..269	CDD:214653	23/86 (27%)
		IGc2	198..258	CDD:197706	20/68 (29%)
		I-set	273..360	CDD:254352	23/104 (22%)
		Ig	290..359	CDD:143165	19/86 (22%)
		FN3	<466..524	CDD:238020	9/30 (30%)
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	26/95 (27%)
		Ig	130..200	CDD:143165	21/69 (30%)
		I-set	226..310	CDD:254352	23/87 (26%)
		IGc2	233..298	CDD:197706	20/68 (29%)
		Ig	313..410	CDD:299845	24/114 (21%)
		IG_like	325..410	CDD:214653	22/102 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810