DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34353 and DIP-eta

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	111/395 - (28%)
Similarity:	182/395 - (46%)	Gaps:	54/395 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 EPMFISRSETFKFITGETIVLPCEVANTDTYVVAWKR--GIAILTAGSVKVTPDPRVRLVNG--- 144
            :|.|.|.........|....|.|.|.:...|.|||.|  ...|||..:..:|.:.|:.:.|.
  Fly    42 DPKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHK 106

  Fly   145 -FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIECSAT 208
             :.::|:|...:|.|.|:|||.|...:.....::::|||.|....|...:.|::||:|.::|:||
  Fly   107 TWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAAT 171

  Fly   209 GNPMPNVTWSRKNNI---LPNGEEKLHSHVLSIE-------NVDRHKGGVYICTANNRVGQPASS 263
            |:|.|.:||.|::.:   |..|||     |:|||       ||.||..|.|:|.|:|.|....|.
  Fly   172 GSPEPTITWRRESGVPIELATGEE-----VMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSK 231

  Fly   264 QVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVI--WFKDTMQL----DTTERHIME 322
            ::.|.|.|.|.|:|:..::.:.||...||.|  ..|..|:.|  |.::..::    .....::.|
  Fly   232 RITLVVHFPPMITVQNQLIGAVEGKGVTLDC--ESEAYPKSINYWTRERGEIVPPGGKYSANVTE 294

  Fly   323 TRGSRHT--LIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPP-----ISQYKDR 380
            ..|.|::  |.|..:...:||:|.|||:|.||....|::|        :..||     :..::.|
  Fly   295 IGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKL--------YRIPPNAVNYVENFEAR 351

  Fly   381 Y---NISWAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGS 442
            :   ..:.:.:||.|.       |......|.:.|.....:..|..:.|...:||:.....|...
  Fly   352 HKGKKRTKSSESHHPA-------RAQEHSGEDMENPGKRKADLSLGAESIDSIYGNSAAGSRRRQ 409

  Fly   443 NMGGL 447
            ::||:
  Fly   410 DLGGV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	24/85 (28%)
		Ig	103..177	CDD:143165	23/79 (29%)
		IG_like	191..269	CDD:214653	33/87 (38%)
		IGc2	198..258	CDD:197706	29/69 (42%)
		I-set	273..360	CDD:254352	27/94 (29%)
		Ig	290..359	CDD:143165	22/76 (29%)
		FN3	<466..524	CDD:238020
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	24/89 (27%)
		IG_like	51..137	CDD:214653	24/85 (28%)
		IG_like	153..237	CDD:214653	33/88 (38%)
		Ig	161..224	CDD:299845	28/67 (42%)
		IG_like	252..335	CDD:214653	25/92 (27%)
		Ig	258..333	CDD:143165	22/76 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810