DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and DIP-beta

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	101/392 - (25%)
Similarity:	161/392 - (41%)	Gaps:	91/392 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 VSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTY-----------VVAWKR 121
            ||....||.|      .||.|:...|......|......|.|.|...:           .|||.:
  Fly    86 VSNKISSVGA------FEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIK 144

  Fly   122 --GIAILTAGSVKVTPDPRVRL----VNGFNLQIRDALPTDAGDYICQIATMDPREI-THTVEIL 179
              ..|||......:|.:.|:.:    .|.:.|.||.....|||.|:||:.| ||.:: |.|:|::
  Fly   145 ADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNT-DPMKMQTATLEVV 208

  Fly   180 VPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNN---ILPNGE------EKLHSHV 235
            :||.|.:..|.|.:.|.:|.|.::.|.|.|:|.|.:||.|::.   |..||.      :.:...:
  Fly   209 IPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEM 273

  Fly   236 LSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGET 300
            |::..:.|.:.|.|:|.|:|.|....|.::.|.|.|.|.:.|...:|.:....:.||:|.|  |.
  Fly   274 LTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNV--EA 336

  Fly   301 QPEVI--WFKDTMQLDTTERHIMETRGSRHTLI--------------IRKVHPQDFGNYSCVAEN 349
            .|:.|  |.::..:        |...|.|:.|.              |:::...|||.|.|:::|
  Fly   337 SPKAINYWQRENGE--------MIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKN 393

  Fly   350 QLGKARKTLQL--SGKPNVAVFNSPPISQ------------------------YKDRYNISWAVD 388
            .:|....|::|  ..:|...:.....:::                        ||||     |.|
  Fly   394 SIGDTEGTIRLYEMERPGKKILRDDDLNEVSKNEVVQKDTRSEDGSRNLNGRLYKDR-----APD 453

  Fly   389 SH 390
            .|
  Fly   454 QH 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	28/97 (29%)
		Ig	103..177	CDD:143165	26/91 (29%)
		IG_like	191..269	CDD:214653	25/86 (29%)
		IGc2	198..258	CDD:197706	20/68 (29%)
		I-set	273..360	CDD:254352	24/102 (24%)
		Ig	290..359	CDD:143165	21/84 (25%)
		FN3	<466..524	CDD:238020
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	31/111 (28%)
		ig	102..195	CDD:278476	23/92 (25%)
		IG_like	219..307	CDD:214653	25/87 (29%)
		Ig	221..307	CDD:299845	24/85 (28%)
		Ig	311..404	CDD:299845	24/102 (24%)
		IG_like	327..405	CDD:214653	21/87 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810