DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG34353 and Dscaml1

DIOPT Version :9

Sequence 1:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001101611.1 Gene:Dscaml1 / 315615 RGDID:1304887 Length:2111 Species:Rattus norvegicus


Alignment Length:543 Identity:121/543 - (22%)
Similarity:209/543 - (38%) Gaps:111/543 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 IAVVSLHFESVSAQSMMTKNEPMFISRS-ETFKFITGETIVLPCEVANTDTYVVAWKRGIAILTA 128
            |..|:..|.|..|..::|..:|:.::.: :..|...|.|::|.|.:..:..:.:.|.|...::..
  Rat   351 ICEVTNTFGSAEANGVLTVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLP 415

  Fly   129 GSVKVTPDPRVRLVNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILV---PPRIHHISTG 190
            |..     ..:|.::...|.|..|..:.:|.|.| .||...:.......|::   .|||  :|:.
  Rat   416 GEA-----ISIRGLSNETLLISSAQKSHSGAYQC-FATRKAQTAQDFAIIVLEDGTPRI--VSSF 472

  Fly   191 GHLQVKKGSSVRIECSATGNPMPNVTWSRKNN-ILPNGEEKLHSHVLSIENVDRH---------K 245
            ....|..|....:.|:|.|.|.|.|||:..:. ::.:|..:.:.:.:|......|         .
  Rat   473 SEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRDGSHRTNQYTMSDGTTISHMNVTGPQIRD 537

  Fly   246 GGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDT 310
            ||||.|||.|.||. |..|..::|...|.|...|.:. :..|.:..:.|.|.|.....:.|:||.
  Rat   538 GGVYRCTARNSVGS-AEYQARINVRGPPSIRAMRNIT-AVAGRDTLINCRVIGYPYYSIKWYKDA 600

  Fly   311 MQLDTTERHIMETRGSRHTLIIRKVHPQDFGNYSC--VAENQLGKARKT-LQLSGKPNVAVFNSP 372
            :.|....|.::...|:.....::|  ..|.|.|.|  :.:.||..::.. :.:...|.:..|..|
  Rat   601 LLLPDNHRQVVFENGTLKLTDVQK--GMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFP 663

  Fly   373 PISQYKDRYNISWAVDS-HSPIEEYKLSFRKLPQGHEVV---GNAIDSSSSSSSMSSSSSQMYGS 433
            |.|..:..| |...|.| ..||   ::::||  .|..::   |..|:|....||:..||..:..:
  Rat   664 PASIGQLLY-IPCVVSSGDMPI---RITWRK--DGQVIISGSGVTIESKEFMSSLQISSVSLKHN 722

  Fly   434 GLH-------AHRIG-----------------SNMGGLSGLSG--SGSYSGYGNVIHWGHNDWRN 472
            |.:       |..:.                 :|..|:.|.:|  :.|..||             
  Rat   723 GNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGY------------- 774

  Fly   473 VVLPAVPVSHHYAQGMSYMVRGLDPDQHYEATVQSRNRYGWSDLTNSFVFSTSSNDGPVDLSTFL 537
               |...|...:|:|..      :|.|::...:..|.:.    |.||              |..:
  Rat   775 ---PPPKVMWKHAKGSG------NPQQYHPVPLTGRIQI----LPNS--------------SLLI 812

  Fly   538 NHGLSDNEMRDLSVTFYGSSAIN 560
            .|.|.::      :.:|...|.|
  Rat   813 RHVLEED------IGYYLCQASN 829

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 17/79 (22%)
Ig 103..177 CDD:143165 14/73 (19%)
IG_like 191..269 CDD:214653 25/87 (29%)
IGc2 198..258 CDD:197706 20/69 (29%)
I-set 273..360 CDD:254352 20/89 (22%)
Ig 290..359 CDD:143165 16/71 (23%)
FN3 <466..524 CDD:238020 10/57 (18%)
Dscaml1NP_001101611.1 IG 101..173 CDD:214652
IGc2 101..168 CDD:197706
Ig 183..276 CDD:299845
IG_like 195..276 CDD:214653
I-set 291..369 CDD:254352 5/17 (29%)
IGc2 298..359 CDD:197706 2/7 (29%)
IGc2 386..447 CDD:197706 14/66 (21%)
I-set 466..560 CDD:254352 29/96 (30%)
Ig 466..556 CDD:299845 28/92 (30%)
IGc2 577..635 CDD:197706 15/59 (25%)
IG_like 665..744 CDD:214653 19/84 (23%)
Ig 673..739 CDD:143165 17/70 (24%)
I-set 748..843 CDD:254352 23/128 (18%)
Ig7_DSCAM 765..843 CDD:143211 20/111 (18%)
I-set 849..942 CDD:254352
Ig 861..949 CDD:299845
FN3 945..1039 CDD:238020
FN3 1046..1143 CDD:238020
fn3 1151..1237 CDD:278470
FN3 1249..1340 CDD:238020
IGc2 1364..1428 CDD:197706
FN3 1442..1532 CDD:238020
FN3 1546..1618 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.