DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34353 and Fas2

DIOPT Version :9

Sequence 1:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster


Alignment Length:576 Identity:125/576 - (21%)
Similarity:210/576 - (36%) Gaps:127/576 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 LAIAVVSLHFE---------SVSAQSMMTKNEPMFISRSETFKFIT------------GETIVLP 106
            ||:.:.||..|         |.:...::.|...:     :|:..||            |:..|:.
  Fly    99 LALMITSLSVEMGGKYYCTASYANTEILEKGVTI-----KTYVAITWTNAPENQYPTLGQDYVVM 158

  Fly   107 CEVANTDTYVVAWKRGIAILTAGSVKVTPDPRVRLVNGFNLQIRDALPTDAGDYICQIATMDPRE 171
            |||.......:.|.|     ....::.|.|..|...||  |.||:...:|.|.|.|:.|.::..|
  Fly   159 CEVKADPNPTIDWLR-----NGDPIRTTNDKYVVQTNG--LLIRNVQESDEGIYTCRAAVIETGE 216

  Fly   172 I---THTVEILVPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSR---KNNILPNGEEK 230
            :   |..||:.:.|.|  ||...:|:..:|......|:|.|.|:|.::|.|   :.|:......:
  Fly   217 LLERTIRVEVFIQPEI--ISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQ 279

  Fly   231 LH--SHVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLV 293
            ::  :.:::|.:|.:...|.|.|.|.||.| ....:..|:||..|:| .|...|......|..:.
  Fly   280 VNPQTGLVTISSVSQDDYGTYTCLAKNRAG-VVDQKTKLNVLVRPQI-YELYNVTGARTKEIAIT 342

  Fly   294 CIVHGETQPEVIWFKDTMQLDTT------------ERHIMETRG-SRHTLIIRKVHPQDFGNYSC 345
            |...|...|.:.:.:...|.:.|            |.:..|.|| |..||.|......|.|.|.|
  Fly   343 CRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQC 407

  Fly   346 VAENQLGKARKT--LQLSGKPNVAVFNS-PPISQYKDR-YNIS-WAVDSHSPIEEYKLSFRKLPQ 405
            :|.|:...|.||  :.:...|:.:.... ||:..::.| .|:| .|:...:...|:..:.||:..
  Fly   408 IARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKD 472

  Fly   406 GHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGSNMGGLS---------------------- 448
            .::.....:.:...|..:....::.|.||...  |.:|:.|.:                      
  Fly   473 LYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKC--IATNIHGTAEHDMQLKEARVPDFVSEAKPSQ 535

  Fly   449 --------GLSGSGSYSGYGNVIHWGHNDWRNVVLPAVPVSHHYAQGMS---------------- 489
                    .:.|..:..|                ||.:..|..|.:.::                
  Fly   536 LTATTMTFDIRGPSTELG----------------LPILAYSVQYKEALNPDWSTAYNRSWSPDSP 584

  Fly   490 YMVRGLDPDQHYEATVQSRNRYGWSDLTNSFVFSTSSNDGPVDLSTFLNHGLSDNE 545
            |:|.||.|...|.....:||:.|..:...:...||.....|.:.....|....|.|
  Fly   585 YIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRSAPEEPKPLHNPVQHDKE 640

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 24/82 (29%)
Ig 103..177 CDD:143165 21/76 (28%)
IG_like 191..269 CDD:214653 20/82 (24%)
IGc2 198..258 CDD:197706 17/64 (27%)
I-set 273..360 CDD:254352 27/101 (27%)
Ig 290..359 CDD:143165 22/83 (27%)
FN3 <466..524 CDD:238020 13/73 (18%)
Fas2NP_001284854.1 IG_like 39..133 CDD:214653 7/38 (18%)
IG_like 144..226 CDD:214653 23/88 (26%)
IGc2 152..209 CDD:197706 19/63 (30%)
I-set 230..319 CDD:254352 24/91 (26%)
IGc2 243..309 CDD:197706 17/65 (26%)
IG_like 330..424 CDD:214653 24/93 (26%)
IGc2 339..412 CDD:197706 18/72 (25%)
Ig 447..518 CDD:143165 13/72 (18%)
fn3 534..611 CDD:278470 15/92 (16%)
FN3 640..735 CDD:238020 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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