DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34353 and zig-2

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	50/213 - (23%)
Similarity:	73/213 - (34%)	Gaps:	59/213 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 PRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRK-------------NNILPNGEEKLHS 233
            |.:....|.....|..|....:.|.|.|.|:|::.|...             .|||.:|::..::
Worm    31 PLLKFTRTPNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNA 95

  Fly   234 HVLS----IENVDRHKGGVYICTANNRV-----------------------GQPASSQVVLHVLF 271
            .::|    |........|.|.|..:|.:                       |.|..|   :.|.|
Worm    96 AMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFIS---MTVDF 157

  Fly   272 SPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFK-DTMQLDTTERHIMETRGSRHTLIIRKV 335
            ..|||          .:...|.|  ..||..|..|.| :.:..:..||:.|...|.   ||||.:
Worm   158 RLEIS----------NNAVALSC--RSETATEWSWHKGEQLLTNDGERYQMFPSGD---LIIRNI 207

  Fly   336 HPQDFGNYSCVAENQLGK 353
            ...|.|.|:|.|.|..|:
Worm   208 SWSDMGEYNCTARNHFGE 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653
		Ig	103..177	CDD:143165
		IG_like	191..269	CDD:214653	21/117 (18%)
		IGc2	198..258	CDD:197706	17/99 (17%)
		I-set	273..360	CDD:254352	25/82 (30%)
		Ig	290..359	CDD:143165	22/65 (34%)
		FN3	<466..524	CDD:238020
zig-2	NP_510069.1	I-set	34..134	CDD:254352	19/99 (19%)
		Ig	34..121	CDD:299845	18/86 (21%)
		Ig	<179..232	CDD:299845	17/50 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900