DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and rig-3

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	491	Identity:	102/491 - (20%)
Similarity:	175/491 - (35%)	Gaps:	99/491 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LPHILF-LAIAVVSLHFESVSAQSMMTKNE--PMFISRSETFKFIT-------GETIVLPCEVAN 111
            |..:|| ||:.   |...:|||....:.||  |:.|| ||...:.|       |:.:::.| |..
Worm     5 LAKMLFPLAMC---LFVSAVSASDSPSSNEANPIVIS-SEAMDYDTNTITVREGKKLMVSC-VFE 64

  Fly   112 TDTYV----VAWKRGIAILTAGSVKVTPDPRVRLV---------NGFNLQIRDALPTDAGDYICQ 163
            :|..:    :.||:.    ...::....:|.:..|         ...:|........|.|.|.|.
Worm    65 SDEQIHKSDLLWKQA----NGNNIDGESNPSLFSVILNEKGSKHRKTSLHFSSVHTRDTGLYTCT 125

  Fly   164 IATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIECSATG----NPMPNVTWSRKNNIL 224
            ..|........|::::|.|.|.............|..:.|:|...|    .||..:|   ..|..
Worm   126 GRTAGGENFEKTIKLVVLPAIEWNDKDTVKGALLGEPITIDCGVKGPSGKEPMIQMT---NGNGE 187

  Fly   225 PNGEE--KLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQ---------VVLHVLFSPEISVE 278
            |..||  .:..:..:|:::.:....:.:......:.|..|.:         |.:.|...||...|
Worm   188 PLDEEIWTIAGNEATIDSLKKEHAELTVSCITIEMHQETSKEEFPVVDRKDVNIEVYTLPEFETE 252

  Fly   279 RPV---VFSGEGHEATLVCIV-------------HGETQPEVIWFKDTMQLDTTERHIMETRGSR 327
            ..|   |......:|.:.|.|             ||:   |.|...|...:..   ::..::|:.
Worm   253 ESVQYTVIDNHVRDAIIYCNVTHSFPPVRHYTFYHGD---EEIKMSDKFNIFV---NVGVSQGAH 311

  Fly   328 HTLIIRKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQYKD-RYNISWAVDSHS 391
              |.|..|:..|.|.|.|.|.|...|:..|:.|. :.|...  .|.::..:| |::|.|.|:|..
Worm   312 --LKIHNVNENDLGTYKCEANNIKAKSYHTIHLR-EANAPA--EPKVTLIEDKRHSIIWKVESID 371

  Fly   392 PIEEYKLSFRKLPQGHEVVGNAIDSSSSSSSMSSSSSQMYGSGLHAHRIGSNMGGLSGLSGSGSY 456
              .:..|....:...|...|.|..|..|...:|.:..:.:...:..:.....:..::||.....|
Worm   372 --RDPDLPMTAVEIRHLRAGTAEASGVSDEDISDAYWKSHSIFMQRNIKDDGIYEINGLRHGHEY 434

  Fly   457 ---------SGYGNVIHWGHNDWRNVVLPAVPVSHH 483
                     :|:|:          :|||.|..:..|
Worm   435 VWRFRQINEAGFGD----------SVVLRAKTLDDH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	15/92 (16%)
		Ig	103..177	CDD:143165	14/86 (16%)
		IG_like	191..269	CDD:214653	15/92 (16%)
		IGc2	198..258	CDD:197706	12/65 (18%)
		I-set	273..360	CDD:254352	25/102 (25%)
		Ig	290..359	CDD:143165	20/81 (25%)
		FN3	<466..524	CDD:238020	5/18 (28%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653	15/98 (15%)
rig-3	NP_509155.1	Ig	267..341	CDD:319273	20/81 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900