DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and zig-8

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	72/340 - (21%)
Similarity:	119/340 - (35%)	Gaps:	112/340 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 RRVGSLPHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGET-IVLPCEVANTDTY 115
            ||..::..||| :....:.|..|....:.:.:......:.|:|...:..|. ..|.|.|.....:
Worm     2 RRFSNICVILF-SFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENPAYLHCSVPPDAEH 65

  Fly   116 VVAWKR---GIAILTAGSVKVTPDPRVRL----VNGFNLQIRDALPTDAGDYICQIATMDPREIT 173
            .:||.|   | |:||||:...|.|||.::    .|.:.|.:|.|...|:|.|:|:|  .|.....
Worm    66 EIAWTRVSDG-ALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDSGCYLCEI--NDKHNTV 127

  Fly   174 HTV--EILVPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNNILPNGEEKLHSHVL 236
            :.|  ::|.||.                           |.|:....:...::.|
Worm   128 YAVYLKVLEPPL---------------------------PSPSSLQKKSTKLMAN---------- 155

  Fly   237 SIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQ 301
                                                          .||:  |..|.|.|....:
Worm   156 ----------------------------------------------MSGD--EVVLNCTVTSTDK 172

  Fly   302 PE----VIWFKD--TMQLDTTERHIMETRGSR----HTLIIRKVHPQDFGNYSCVAENQLGKARK 356
            .|    |:|.:|  |:..:.||::|::.:...    .|:.|||...:|.|||:|  |:...||.:
Worm   173 DEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYAC--EHSQQKASQ 235

  Fly   357 TLQLSGKPNVAVFNS 371
            .:.:: |......||
Worm   236 IVHIN-KAEAQTSNS 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	28/89 (31%)
		Ig	103..177	CDD:143165	27/82 (33%)
		IG_like	191..269	CDD:214653	3/77 (4%)
		IGc2	198..258	CDD:197706	3/59 (5%)
		I-set	273..360	CDD:254352	26/96 (27%)
		Ig	290..359	CDD:143165	23/78 (29%)
		FN3	<466..524	CDD:238020
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	27/81 (33%)
		Ig	55..129	CDD:143165	26/76 (34%)
		ig	158..229	CDD:278476	23/74 (31%)
		IG_like	158..227	CDD:214653	22/72 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810