DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and iglon5

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	87/304 - (28%)
Similarity:	139/304 - (45%)	Gaps:	39/304 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 FISRSETFKFITGETIVLPCEVANTDTYVVAWKRGIAILTAGSVKVTPDPRVRLVNG----FNLQ 148
            |:..::.:....|:...|.|.:.:..|. |||.....||.||..|.:.|.||:|:..    :::.
Frog    29 FVPPADNYTVSQGDNATLSCLIDDKVTR-VAWLNRSNILYAGKDKWSIDSRVQLLTNTKSEYSIV 92

  Fly   149 IRDALPTDAGDYICQIATMDPREITHTVEIL----VPPRIHHISTGGHLQVKKGSSVRIECSATG 209
            |......|.|.|.|...|.|.   .||.::.    ||.:|.:||:.  :.|.:||:|.::|.|.|
Frog    93 ITHVDVADEGLYTCSFQTEDK---PHTSQVYLIVQVPAKIVNISSS--VTVNEGSNVNLQCLAVG 152

  Fly   210 NPMPNVTWSR-KNNILPNGEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSP 273
            .|.|.:||.: .......||      :|.|..::|.:.|.|.|..:|.|..|.:.:|.:.|.:.|
Frog   153 KPEPTITWQQLSEGFSSEGE------LLEITEINRQQAGDYECVTSNGVSVPDTKKVQITVNYPP 211

  Fly   274 EI----SVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDTMQ--LDTTERHIMETRGSRHTLII 332
            .|    :.:.||     |..|||.|........|..|:||..:  :..||...::|..|...::.
Frog   212 YITDVKNAQSPV-----GRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIKTESSWSVIVF 271

  Fly   333 RKVHPQDFGNYSCVAENQLGKARKTLQLSGKPNVAVFNSPPISQ 376
            ..|..:.:|||:|:|.|:||....:|:|. ||      ..|::|
Frog   272 SNVTSRHYGNYTCLASNKLGSFNSSLRLL-KP------GDPLNQ 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	25/87 (29%)
		Ig	103..177	CDD:143165	24/77 (31%)
		IG_like	191..269	CDD:214653	23/78 (29%)
		IGc2	198..258	CDD:197706	19/60 (32%)
		I-set	273..360	CDD:254352	27/92 (29%)
		Ig	290..359	CDD:143165	21/70 (30%)
		FN3	<466..524	CDD:238020
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	25/95 (26%)
		IG_like	35..123	CDD:214653	25/91 (27%)
		Ig	126..207	CDD:299845	27/88 (31%)
		I-set	128..207	CDD:254352	26/86 (30%)
		I-set	210..299	CDD:254352	27/93 (29%)
		Ig	227..298	CDD:143165	21/70 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910