DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and kirrel1b

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_017212964.1	Gene:	kirrel1b / 100170816	ZFINID:	ZDB-GENE-070912-173	Length:	801	Species:	Danio rerio

Alignment Length:	508	Identity:	105/508 - (20%)
Similarity:	172/508 - (33%)	Gaps:	149/508 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 SLPHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYVVAW- 119
            |:..:..:.:|::|:|         ...:.|.|.........:.||.:||.|.|.|. |.:|.|
Zfish     4 SMTCLWIVTLAIISVH---------RVFSGPRFSQEPADQSVVIGERVVLSCVVFNY-TGIVQWT 58

  Fly   120 KRGIAILTAGSVKVTPDPRV-RL--VNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILVP 181
            |.|:|:.....::..|..|| |:  |..:||:|..|..||...|.||......|.....:.:|:|
Zfish    59 KDGLALGIGEDLRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQATEAALRSRRAKLTVLIP 123

  Fly   182 PRIHHISTGGHLQVKKGSSVRIECSATG-NPMPNVTWSR----------KNNILPNGEEKLHSHV 235
            |....|.....:.:..|:|..:.|.:.| .||..:.|.:          ...:|.:.:.......
Zfish   124 PDGPVIEGSPEILLTAGTSFNLTCVSRGAKPMSTIEWYKDGIIVEGAHTSTEVLSDRKRVTTKSF 188

  Fly   236 LSIENVDRHKGGVYICTANNRVGQPAS--SQVVLHVLFSPEI--SVE-RPVVFSGEGHEATLVCI 295
            |.|:.:|...|..:.|.|:| :..|..  |.|.|::...|.:  |:| |.|:   ||......|
Zfish   189 LEIQPMDTDTGRNFTCVASN-LAAPLGKRSTVTLNIHHPPTVILSIEPRSVL---EGERVKFTC- 248

  Fly   296 VHGETQPEVI---WFKDTMQLDTTERHIMET---------------------------------- 323
             .....|.::   |.|..:.||.....:.||
Zfish   249 -QATANPPIMGYRWAKGGVILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGP 312

  Fly   324 -----------------------------------RGS------RHTLIIRKVHPQDFGNYSC-- 345
                                               :||      .:.|.::.|...|.|.|.|
Zfish   313 ILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKA 377

  Fly   346 -VAENQLGKARKTLQLSGKPNVAVFNSPPISQYKDR--------YNIS---------------WA 386
             |....:|:...||.::|.|   :.:|.|| ||..|        |..|               |.
Zfish   378 IVPRIGVGETEVTLTVNGPP---IISSEPI-QYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWE 438

  Fly   387 VDSHSPIEEYKL-SFRKLPQGHEVVG----NAIDSSSSSSSMSSSSSQMYGSG 434
            .:..:.:|.|.: ..|...||..|:.    |.:..:...|:.:.::...:|.|
Zfish   439 KERGTLLERYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPG 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	28/83 (34%)
		Ig	103..177	CDD:143165	26/77 (34%)
		IG_like	191..269	CDD:214653	19/90 (21%)
		IGc2	198..258	CDD:197706	15/70 (21%)
		I-set	273..360	CDD:254352	27/170 (16%)
		Ig	290..359	CDD:143165	19/149 (13%)
		FN3	<466..524	CDD:238020
kirrel1b	XP_017212964.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810