DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34353 and si:dkey-11p23.7

DIOPT Version :9

Sequence 1:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001095865.1	Gene:	si:dkey-11p23.7 / 100006927	ZFINID:	ZDB-GENE-100922-120	Length:	287	Species:	Danio rerio

Alignment Length:	213	Identity:	52/213 - (24%)
Similarity:	86/213 - (40%)	Gaps:	43/213 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 ITGETIVLPCEV-----ANTDTYVVAWKRG-----IAILTAGSV--------KVTPDPRVRLV-- 142
            |.|..:||||..     .:..:..|:|..|     :.:....|:        |...|.|.||.
Zfish    39 IEGYPVVLPCSFTHPHHTHPSSMYVSWTLGHGRAAVLLFRCSSLNNSQLCQSKPNQDQRYRLEGN 103

  Fly   143 ---NGFNLQIRDALPTDAGDYICQIA------TMDPREITHTVEILVPPRIHHISTGGHLQVKKG 198
               :..:|::......|:|.|.|::.      |.....:...:.:...|||..:|..|    .:.
Zfish   104 HRNHDISLRVNSLTLKDSGRYYCRVELPGHQHTSFENTLGTRLRVEAAPRILSLSAEG----SEI 164

  Fly   199 SSVRIECSATGNPMPNVTWSRKNNIL------PNGEEKLHSHVLSIENVDRHKGGVYICTANNRV 257
            |..:..|...|:|:|:|.|...|.:|      |..::....:..|.:.:|...||.|||.|:|.:
Zfish   165 SGFKAVCEVQGSPLPDVQWIAPNGVLDGDAAFPLSQDTAGQYRASSQLLDVQPGGQYICAASNSL 229

  Fly   258 GQPASSQVVLHVLF-SPE 274
            |:   .|..|::|. |||
Zfish   230 GK---DQATLYLLCPSPE 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	20/108 (19%)
		Ig	103..177	CDD:143165	19/102 (19%)
		IG_like	191..269	CDD:214653	23/83 (28%)
		IGc2	198..258	CDD:197706	19/65 (29%)
		I-set	273..360	CDD:254352	2/2 (100%)
		Ig	290..359	CDD:143165
		FN3	<466..524	CDD:238020
si:dkey-11p23.7	NP_001095865.1	IG_like	33..148	CDD:214653	21/108 (19%)
		V-set	33..148	CDD:284989	21/108 (19%)
		Ig	150..238	CDD:299845	27/94 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910