Protein Alignment CG34370 and bmp1a

DIOPT Version :10

• Sequence 1: NP_995921.2
• Gene: CG34370 / 5740565
• FlyBaseID: FBgn0085399
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001035126.1
• Gene: bmp1a / 572452
• ZFINID: ZDB-GENE-060818-1
• Length: 986
• Species: Danio rerio
• Alignment Length: 812
• Identity: 170/812 - (20%)
• Similarity: 282/812 - (34%)
• Gaps: 244/812 - (30%)

  Fly    69 SSSDVSRDH----CNKTVDIFED----ISSPEVSNQNVGRPLTCWYRFRTLKGAPRDFVLRLRFK 125
            |..|:::..    |.:..|..::    .|||...| .....:.|.:|.....|  ...:|
Zfish   295 SKGDIAQARKLYKCPRCGDSLQESSGNFSSPGYPN-GYSAYMHCIWRISVTPG--EKIIL----- 351

  Fly   126 KFKVGQLLNATHCEGGYLQIVDGNAKTDVSNRREP--GMFCGEAEQPQTFISETSYVKVLFH-TD 187
            .|....|..:..|...:::|.||..      |:.|  |.|||: :.|...||..|.:.:.|. :.
Zfish   352 NFTSMDLYRSHLCWYDHVEIRDGYW------RKAPLKGRFCGD-KLPDPIISTDSRLWIEFRSSS 409

  Fly   188 NFTDQTYFTFDSRAEQQTEVYLRYGQHPELYPNRRGEVVQGSYCEREYRDCRLQTCYVQSPAYPG 252
            |:..:.:          :.||               |.:.|...:::       ...:|||.||.
Zfish   410 NWVGKGF----------SAVY---------------EAICGGEVKKD-------NGQIQSPNYPD 442

  Fly   253 LYPRALNCRYKLHTRQPYIKLYLQNEQFAVDGQRCENVMTCPIRPIGSGNEHCPYDWLAVYDGRD 317
            .|.....|.:|:...|.| .:.|..:.|.::                 .:::|.||:|.|.||..
Zfish   443 DYRPNKVCVWKITVAQGY-HVGLTFQSFEIE-----------------RHDNCAYDYLEVRDGNS 489

  Fly   318 EHSPLIGKFCGLGKFPFSIIGTSQYMYVEFVTSPAGPLLNTGFHFNV------GNWPGH------ 370
            |.|||:|:|||..| |..|..:|..::::||:.  |.:...||..|.      .:.|.:
Zfish   490 ESSPLLGRFCGYDK-PDDIKSSSNQLWMKFVSD--GSVNKAGFAANFFKEMDECSRPDNGRCEQR 551

  Fly   371 -VETAGIKHGVCD--WLLSSDSLKDSSASEGIF------LSIAHW---YPPNTSCSYHIKGHVGE 423
             |.|.|.....||  :.|::|.....:|..|..      ::...|   ||||.:|.:.:......
Zfish   552 CVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPKEYPPNKNCIWQLVAPTQY 616

  Fly   424 IVRLYFPSFRI--NRIESPILKYEGDCGESLTIYDSDHADPARIIKTFCDTFSRPMEKVDFVSTS 486
            .:.|.|..|..  |.:.:..|...|.|........|..:..:|:...||..     ||.:.:::.
Zfish   617 RITLLFDVFETEGNDVSTRFLPLRGVCKYDFVEVRSGLSADSRLHGKFCGA-----EKPEAITSQ 676

  Fly   487 -PSLYVQFDS-KTGSYSGSSLYYWAHYDFFNNTRFGDPVPNTLCDEVMYAWKHPGGRLRSPLNSL 549
             .::.::|.| .|.|..|           |....|.|.      ||..   |..||.....:|:.
Zfish   677 YNNMRIEFKSDNTVSKKG-----------FKAQFFSDK------DECS---KENGGCQHECVNTF 721

  Fly   550 IFKRTGGSDVRCQYKFVTDRRLY----ARAIIEVNSVS-------FKELPYNSNACTRC------ 597
                 |....:|:..||.....:    |.....|||||       :.:...:..|||..
Zfish   722 -----GSYSCQCRSGFVLHENKHDCKEAGCDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPG 781

  Fly   598 HEERV---------------DKLVIWEERDKYQNNLACFCDNIPRAVRVISSADQMNLEMIVQGQ 647
            |..::               |.:.|::.||....:|..:| ...:...:||:.::|.:.
Zfish   782 HRIKIAFNEIDMEPHLECAYDHIEIYDGRDSKAQSLGRYC-GTKKPQPIISTGNKMFIR------ 839

  Fly   648 HAITSYFKNPNPLFEATYEFAHGPLCGPITLGPSPDGELVFPYKKALAMVSGPMAPPEHHYRREK 712
                  |.:.|.:.:..:|.:|...||         |.|     ||
Zfish   840 ------FFSDNSVQKKGFEASHTAECG---------GRL-----KA------------------- 865

  Fly   713 CIWELKVAAQRDLWLNLEKARFADRSCDSAKIEVYLAGRLEPRFVVCPE---NISLA-RDLPILT 773
               |:|.   :||:   ..|:|.|.:         ..|..:.::|:..|   .:.|. :...|..
Zfish   866 ---EVKT---KDLY---SHAQFGDNN---------YPGASDCQWVITAEKGYGVELIFQTFEIEE 912

  Fly   774 TAELG------ATGADQEPLPVLIQYTGDGQP 799
            .|:.|      ..|||.:. |.|.:|.|.|.|
Zfish   913 EADCGYDYMELFDGADTKS-PRLGRYCGSGPP 943

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34370	NP_995921.2	CUB	88..195	CDD:238001	26/109 (24%)
		CUB	244..363	CDD:238001	36/118 (31%)
		CUB	407..509	CDD:238001	23/105 (22%)
bmp1a	NP_001035126.1	ZnMc_BMP1_TLD	112..309	CDD:239808	2/13 (15%)
		CUB	311..420	CDD:395345	27/133 (20%)
		CUB	424..533	CDD:395345	37/136 (27%)
		FXa_inhibition	544..576	CDD:464251	7/31 (23%)
		CUB	580..699	CDD:395345	26/134 (19%)
		FXa_inhibition	706..741	CDD:464251	8/42 (19%)
		CUB	746..855	CDD:395345	21/121 (17%)
		CUB	859..972	CDD:395345	29/137 (21%)