Protein Alignment CG34370 and tok

DIOPT Version :10

• Sequence 1: NP_995921.2
• Gene: CG34370 / 5740565
• FlyBaseID: FBgn0085399
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_476879.1
• Gene: tok / 42944
• FlyBaseID: FBgn0004885
• Length: 1464
• Species: Drosophila melanogaster
• Alignment Length: 814
• Identity: 167/814 - (20%)
• Similarity: 290/814 - (35%)
• Gaps: 228/814 - (28%)

  Fly    69 SSSDVSRDH----CNKTVDIFEDIS----SPE------VSNQNVGRPLTCWYRFRTLKGAPRDFV 119
            |..|:::.:    |.|....|::.|    ||.      :||:..    .|.:|.....|.
  Fly   707 SQGDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGALSNETE----HCEWRITATYGE----- 762

  Fly   120 LRLRFKKFKVGQLLNATHCEGGYLQIVDGNAKTDVSNRREP--GMFCGEAEQPQTFISETSYVKV 182
             |:..|...: .:..:.:||..||:|.||..:      :.|  |.|||:.:: :...:|:|.: :
  Fly   763 -RVELKLENM-NIFKSNNCETDYLEIRDGYFE------KSPLIGRFCGKVDK-EVIRTESSRM-L 817

  Fly   183 LFHTDNFTDQTYFTFDSRAEQQTEVYLRYGQHPELYPNRRGEVVQGSYCEREYRDCRLQTCYVQS 247
            |.:.:....:.:..|  :||                    .:||.|.....:....||     :|
  Fly   818 LTYVNTHRIEGFRGF--KAE--------------------FDVVCGGELSVDDAVGRL-----ES 855

  Fly   248 PAYPGLYPRALNCRYKLHTRQPYIKLYLQNEQFAVDGQRCENVMTCPIRPIGSGNEHCPYDWLAV 312
            |.||..|.....|.:|:...:.| ::.|:.:.|.|:                 .::.|.||::.|
  Fly   856 PNYPLDYLPNKECVWKITVPESY-QVALKFQSFEVE-----------------NHDSCVYDYVEV 902

  Fly   313 YDGRDEHSPLIGKFCGLGKFPFSIIGTSQYMYVEFVTSPAGPLLNTGFHFNVGNWPGHVETA--G 375
            .||..:.:||||.|||. |.|.::..:...|||:||:..:  :...||...........||.  |
  Fly   903 RDGPGQDAPLIGVFCGY-KPPPNMKSSGNSMYVKFVSDTS--VQKAGFSAVFMKEVDECETQNHG 964

  Fly   376 IKHGVCDWL------------LSSDSLKDSSASEGIF---------LSIAHWYPPNTSCSYHIKG 419
            .:|...:.|            |.||......|..|:.         .|....||....|.:.|..
  Fly   965 CEHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNGTITSPSFPEMYPLLKECIWEIVA 1029

  Fly   420 HVGEIVRLYFPSFRINRIESPILKYEGDCG-ESLTIYDSDHADPARIIKTFCDTFSRPMEKVDFV 483
            .....:.|.|..|.:    ......:.||| :|:|:|.....:..:.|.|||.:...|..    .
  Fly  1030 PPKHRISLNFTHFDL----EGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTA----T 1086

  Fly   484 STSPSLYVQFDS-KTGSYSGSSLYYWAHYD--FFNNTRFGDPVPNTL------------------ 527
            |.|.:|.::|.| |:...||.:..::...|  ..||........||:
  Fly  1087 SESNALRLEFHSDKSIQRSGFAAVFFTDIDECAVNNGGCQHECRNTIGSYICMCHNGYSMHENGH 1151

  Fly   528 -C--DEVMYAWKHPGGRLRSPLNSLIFKRTGGSDVRCQYKFVTDRRLYARAIIEVNSVSFKELPY 589
             |  .|..|....|.|.:.||    .:..:...:..|.:.|:|......:.|       |.|...
  Fly  1152 DCKEGECKYEISAPFGTIFSP----NYPDSYPPNADCVWHFITTPGHRIKLI-------FNEFDV 1205

  Fly   590 NSNACTRCHEE-RVDKLVIWEERDKYQNNLACFC-DNIPRAVRVISSADQMNLEMIVQGQHAITS 652
            .|      |:| ..|.:.:::...:..:.|..|| |.||  ..:.|:::||  .|:::     |.
  Fly  1206 ES------HQECTYDNVAVYDGESESSSVLGRFCGDKIP--FPISSTSNQM--YMVLK-----TD 1255

  Fly   653 YFKNPNPLFEATYEFAHGPLCGPITLGPSPDGELVFPYKKALAMVSGPMAPPEHHYRREK----- 712
            ..|..|     .:..:|...||              .|.:|.:.|       :..|...:
  Fly  1256 KNKQKN-----GFTASHSTACG--------------GYLRATSQV-------QQFYSHARFGNQD 1294

  Fly   713 ------CIWELKVAAQRDLWLNLEKARF---ADRSCDSAKIEVY-----LAGRLEPRFVVCPENI 763
                  |.|  .:||..:.::.|....|   :..:|....::|:     :.|:..|.:.....|:
  Fly  1295 YDDGMDCEW--TIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNV 1357

  Fly   764 SLARDLPILTTAELGATGADQEPLPVLIQYTGDG 797
             |.:|:..:|.:             :|:::..||
  Fly  1358 -LPQDINSMTHS-------------LLVRFKTDG 1377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34370	NP_995921.2	CUB	88..195	CDD:238001	25/118 (21%)
		CUB	244..363	CDD:238001	33/118 (28%)
		CUB	407..509	CDD:238001	26/103 (25%)
tok	NP_476879.1	ZnMc_BMP1_TLD	520..721	CDD:239808	2/13 (15%)
		CUB	723..836	CDD:412131	29/153 (19%)
		CUB	840..951	CDD:395345	36/136 (26%)
		FXa_inhibition	958..993	CDD:464251	8/34 (24%)
		CUB	997..1111	CDD:395345	28/121 (23%)
		FXa_inhibition	1118..1153	CDD:464251	4/34 (12%)
		CUB	1158..1267	CDD:395345	28/139 (20%)
		CUB	1271..1390	CDD:238001	23/144 (16%)