Protein Alignment CG34448 and PNLIP

DIOPT Version :10

• Sequence 1: NP_001097059.1
• Gene: CG34448 / 5740554
• FlyBaseID: FBgn0085477
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 114/367 - (31%)
• Similarity: 158/367 - (43%)
• Gaps: 68/367 - (18%)

  Fly     6 TLILLLTIV-------------------SGFCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTN 51
            ||.|||..|                   ||..:...|...|.|        |..|:|  |.||||
Human     6 TLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSP--------KDVNTR--FLLYTN 60

  Fly    52 QTRDD--PIQLDPLNPQKDVFQPRLPLKILIHGFI--GNRNLTPNLEVRDVLLQTQPINVISVDY 112
            :..::  .:..|..:.....|:.....:.:|||||  |..|...|  |...|.:.:.:|.|.||:
Human    61 ENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLAN--VCKNLFKVESVNCICVDW 123

  Fly   113 --GTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVANYVSQ 175
              |:...    |..|..|..||...:|..:..|.||......::|:||.||||..||......:.
Human   124 KGGSRTG----YTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNG 184

  Fly   176 PLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTD--PFF----FSMLPPMGHADFYPNLD 234
            .:.||||||||.|.|...|.| .:||.|||.|||:||||  |..    |.|...:||.||:|| .
Human   185 TIGRITGLDPAEPCFQGTPEL-VRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPN-G 247

  Fly   235 QLNQRGC-----SYISN----WR----FYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQR 286
            .:...||     |.|.:    |.    |..|||.|:..||.:||::..||....|..:..|.:.:
Human   248 GVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANK 312

  Fly   287 CSHYSNMPNTQMGYFV------SEDASGSYFLTTHEVAPFAK 322
            |....:....|||::.      :.|....::|.|.:.:.||:
Human   313 CFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFAR 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34448	NP_001097059.1	Pancreat_lipase_like	44..316	CDD:238363	98/302 (32%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:395099	106/352 (30%)
		PLAT_PL	355..465	CDD:238857	114/367 (31%)