Protein Alignment CG34448 and LIPC

DIOPT Version :10

• Sequence 1: NP_001097059.1
• Gene: CG34448 / 5740554
• FlyBaseID: FBgn0085477
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_000227.2
• Gene: LIPC / 3990
• HGNCID: 6619
• Length: 499
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 99/329 - (30%)
• Similarity: 146/329 - (44%)
• Gaps: 79/329 - (24%)

  Fly    43 RVSFWLYTNQTRDDPIQLD-PLNPQKDVFQPRLPLKILIHGFIGNRNLTPNLEVRDVL------- 99
            :..|.|:....:...|::: |...|:..|...|||.::|||:          .|..||
Human    49 KTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGW----------SVDGVLENWIWQM 103

  Fly   100 ------LQTQPINVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIG 158
                  ...||:||..||:.||..  .:|..||.|..:|.:.:|.::..|..:....|..:||||
Human   104 VAALKSQPAQPVNVGLVDWITLAH--DHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIG 166

  Fly   159 FSLGAQVAGMVANYV--SQPLARITGLDPAGPGFM-MQPSLQQKLDASDADFVDIIHTDPFFFS- 219
            :||||.|:|...:.:  :..:.||||||.|||.|. ..||  .:|...||:|||.|||    |:
Human   167 YSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPS--NRLSPDDANFVDAIHT----FTR 225

  Fly   220 --------MLPPMGHADFYPNLDQLNQRGCSYISNWRF-----YN-------CNHYRAAVYYGES 264
                    :..|:||.|||||.... |.||.::..:|.     :|       |:|.|:...:.:|
Human   226 EHMGLSVGIKQPIGHYDFYPNGGSF-QPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDS 289

  Fly   265 II-SERGFWAQQCGGWFDFFSQ---------RCSHYSNMPNTQMGYFVSED---ASGSYFLTTHE 316
            :: :.....|..||. .:.|||         ||       || :||.|.::   .|...||.|..
Human   290 LLHAGTQSMAYPCGD-MNSFSQGLCLSCKKGRC-------NT-LGYHVRQEPRSKSKRLFLVTRA 345

  Fly   317 VAPF 320
            .:||
Human   346 QSPF 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34448	NP_001097059.1	Pancreat_lipase_like	44..316	CDD:238363	97/322 (30%)
LIPC	NP_000227.2	Lipase	24..349	CDD:395099	97/327 (30%)
		Essential for determining substrate specificity. /evidence=ECO:0000269|PubMed:7592706	254..277		3/22 (14%)
		PLAT_LPL	352..487	CDD:238856